Journal ArticleDOI
The reaction of no with superoxide
Robert E. Huie,S. Padmaja +1 more
- Vol. 18, Iss: 4, pp 195-199
TLDR
The rate constant for the reaction of NO with .O2- was determined to be (6.7 +/- 0.9) x 10(9) l mol-1 s-1, considerably higher than previously reported.Abstract:
The rate constant for the reaction of NO with ·O2− was determined to be (6.7 ± 0.9) × 109 1 mol−1 s−1, considerably higher than previously reported. Rate measurements were made from pH 5.6 to 12.5 ...read more
Citations
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Nitric Oxide and Peroxynitrite in Health and Disease
TL;DR: Current evidence indicates that most of the cytotoxicity attributed to NO is rather due to peroxynitrite, produced from the diffusion-controlled reaction between NO and another free radical, the superoxide anion, which is presented in detail in this review.
Journal ArticleDOI
Cell biology and molecular basis of denitrification.
TL;DR: Denitrification is intimately related to fundamental cellular processes that include primary and secondary transport, protein translocation, cytochrome c biogenesis, anaerobic gene regulation, metalloprotein assembly, and the biosynthesis of the cofactors molybdopterin and heme D1.
Journal ArticleDOI
Oxidative stress and neurodegenerative diseases: a review of upstream and downstream antioxidant therapeutic options.
TL;DR: Recognition of upstream and downstream antioxidant therapy to oxidative stress has been proved an effective tool in alteration of any neuronal damage as well as free radical scavenging.
Journal ArticleDOI
Reactive oxygen species in cell signaling
TL;DR: The evidence for ligand-induced generation of ROS, its cellular sources, and the signaling pathways that are activated is examined.
Journal ArticleDOI
Damage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancer.
Helen Wiseman,Barry Halliwell +1 more
TL;DR: ROS and RNS could contribute to the initiation of cancer, in addition to being important in the promotion and progression phases, as evidence is growing that antioxidants may prevent or delay the onset of some types of cancer.
References
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Journal ArticleDOI
Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor
TL;DR: NO released from endothelial cells is indistinguishable from EDRF in terms of biological activity, stability, and susceptibility to an inhibitor and to a potentiator.
Journal ArticleDOI
Critical Review of rate constants for reactions of hydrated electrons, hydrogen atoms and hydroxyl radicals (⋅OH/⋅O− in Aqueous Solution
TL;DR: In this article, the rate constants for over 3500 reaction are tabulated, including reaction with molecules, ions and other radicals derived from inorganic and organic solutes, and the corresponding radical anions, ⋅O− and eaq−, have been critically pulse radiolysis, flash photolysis and other methods.
Journal Article
Critical review of rate condtants for reaction of hydrated electrons, hydrogen atoms and hydroxyl radicals in aqueous solution
Journal ArticleDOI
Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.
TL;DR: It is proposed that superoxide dismutase may protect vascular tissue stimulated to produce superoxide and NO under pathological conditions by preventing the formation of peroxynitrite.
Chemical kinetics and photochemical data for use in stratospheric modeling
W. B. Demore,J. J. Margitan,Mario J. Molina,R. T. Watson,D. M. Golden,R. F. Hampson,Michael J. Kurylo,Carleton J. Howard,A. R. Ravishankara +8 more
TL;DR: As part of a series of evaluated sets, rate constants and photochemical cross sections compiled by the NASA Panel for Data Evaluation are provided in this article, with particular emphasis on the ozone layer and its possible perturbation by anthropogenic and natural phenomena.