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Journal ArticleDOI

The relationship between mental and physical health: Insights from the study of heart rate variability

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TLDR
This work shows that otherwise healthy, unmedicated patients with these disorders display reduced resting-state HRV, and that pharmacological treatments do not ameliorate these reductions, and proposes a working model for the effects of mood disorders, comorbid conditions, and their treatments to help guide future research activities.
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This article is published in International Journal of Psychophysiology.The article was published on 2013-09-01. It has received 412 citations till now. The article focuses on the topics: Mood disorders & Psychological intervention.

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Citations
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Heart rate variability as a marker of healthy ageing.

TL;DR: These findings suggest that an age-related decline in HRV is not inevitable, and longitudinal designs exploring within-individual changes in cardiac vagal tone are required to better understand the factors contributing to healthy ageing.
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Resting state vagal tone in attention deficit (hyperactivity) disorder: A meta-analysis

TL;DR: Unlike a variety of internalising psychiatric disorders, ADHD is not associated with altered short-term measures of resting-state vagal tone.
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Self-regulation and aggressive antisocial behaviour: insights from amygdala-prefrontal and heart-brain interactions

TL;DR: Neuroimaging and physiology research on heart-brain interactions offers new insights in to the role of self-regulation in aggressive and antisocial behaviour, and for understanding who might benefit the most from interventions aimed at improving self- regulation.
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An integrated approach to understand biological stress system dysregulation across depressive and anxiety disorders

TL;DR: In this article, the authors investigated whether current or remitted depressive and/or anxiety disorders, including specific symptom profiles, were associated with separate markers and cumulative indexes of the HPA-axis, immune system, autonomic nervous system (ANS), and heart rate, respiratory sinus arrhythmia, pre-ejection period.
References
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Journal ArticleDOI

Prevalence, Severity, and Comorbidity of 12-Month DSM-IV Disorders in the National Comorbidity Survey Replication

TL;DR: Although mental disorders are widespread, serious cases are concentrated among a relatively small proportion of cases with high comorbidity, as shown in the recently completed US National Comorbidities Survey Replication.
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Projections of Global Mortality and Burden of Disease from 2002 to 2030

TL;DR: These projections represent a set of three visions of the future for population health, based on certain explicit assumptions, which enable us to appreciate better the implications for health and health policy of currently observed trends, and the likely impact of fairly certain future trends.
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From inflammation to sickness and depression: when the immune system subjugates the brain

TL;DR: In response to a peripheral infection, innate immune cells produce pro-inflammatory cytokines that act on the brain to cause sickness behaviour, which can lead to an exacerbation of sickness and the development of symptoms of depression in vulnerable individuals.
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The inflammatory reflex

Kevin J. Tracey
- 19 Dec 2002 - 
TL;DR: The discovery that cholinergic neurons inhibit acute inflammation has qualitatively expanded understanding of how the nervous system modulates immune responses, and the opportunity now exists to apply this insight to the treatment of inflammation through selective and reversible 'hard-wired' neural systems.
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Global burden of disease and injury and economic cost attributable to alcohol use and alcohol-use disorders.

TL;DR: The burden of mortality and disease attributable to alcohol, both globally and for ten large countries, is quantified and concludes that alcohol consumption is one of the major avoidable risk factors, and actions to reduce burden and costs associated with alcohol should be urgently increased.
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