The structure and biologic activities of plasma fibronectin
MW Mosesson,DL Amrani +1 more
TLDR
This review is concerned with providing a concise critical summary of the structure and biologic activities of fibronectin, mainly the plasma form, but consideration of other forms of the protein is also included wherever such information lends clarity or interpretive value.About:
This article is published in Blood.The article was published on 1980-08-01 and is currently open access. It has received 408 citations till now. The article focuses on the topics: Fibronectin.read more
Citations
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Journal ArticleDOI
Role of collagenous matrices in the adhesion and growth of cells.
TL;DR: Current knowledge of the types of collagen and their distribution and biosynthesis is outlined, including fibronectin, which not only functions as an attachment protein, but also may play an important role in repair reactions.
Journal ArticleDOI
Fibronectins: multifunctional modular glycoproteins.
TL;DR: The current understanding of the structure and properties of fibronectins is reviewed to focus on overall concepts, recent developments and promising future research directions in this rapidly expanding field.
Journal ArticleDOI
Parameters influencing the stealthiness of colloidal drug delivery systems.
TL;DR: In this article, the interaction of opsonins and the macrophage plasma membrane with the surface of a colloidal drug delivery system (CDDS) was investigated. And the authors focused on parameters influencing the interactions of opticins and macrophages.
Journal Article
Effect of Plasminogen Activator (Urokinase), Plasmin, and Thrombin on Glycoprotein and Collagenous Components of Basement Membrane
Lance A. Liotta,Ronald H. Goldfarb,R. Brundage,Gene P. Siegal,V.P. Terranova,Spiridione Garbisa +5 more
TL;DR: These BM components are poor substrates for plasminogen activators and that plAsmin alone is not sufficient to completely degrade the whole BM, suggesting that laminin, but not type IV collagen, was removed from the wholeBM by plasmine treatment.
Journal ArticleDOI
Fibronectin adsorption on hydrophilic and hydrophobic surfaces detected by antibody binding and analyzed during cell adhesion in serum-containing medium.
TL;DR: The adsorption of plasma FN onto both hydrophobic and hydrophilic surfaces from serum-containing solutions was found to depend on the serum concentration, suggesting the possibility that in long term cultures, cells deposit endogenous spreading factors on top of or in place of the adsorbed non-fibronectin serum proteins.
References
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Journal ArticleDOI
Binding of soluble form of fibroblast surface protein, fibronectin, to collagen.
Eva Engvall,Erkki Ruoslahti +1 more
TL;DR: The findings suggest the possibility that Malignantly transformed fibroblasts lack surface fibronectin, which results in a lack of anchorage to the surrounding intercellular matrix, which could contribute to the malignant growth behavior.
Book ChapterDOI
Cellular adhesiveness and extracellular substrata.
TL;DR: Adhesiveness is common to many different cell types under a variety of conditions, and the underlying mechanisms are analogous for active cell-substratum adhesion occurring in vitro to artificial and to model physiological substrata and in vivo to fibr inogen or fibrin deposits.
Book ChapterDOI
The epsilon-(gamma-glutamyl)lysine crosslink and the catalytic role of transglutaminases.
J.E. Folk,J.S. Finlayson +1 more
TL;DR: This chapter describes the current knowledge of the distribution, formation, and function of the ɛ-(γ-glutamyl)lysine crosslink, and focuses largely on the crosslink known to be or believed to be formed by the catalytic action of transglutaminases.
Journal ArticleDOI
Affinity of fibronectin to collagens of different genetic types and to fibrinogen.
E Engvall,E Ruoslahti,E J Miller +2 more
TL;DR: It is proposed that cell surface fibronectin mediates attachment of cells to the collagenous extracellular matrix and to a temporary fibrin matrix in a wound.
Journal ArticleDOI
Fibronectin binds to Staphylococcus aureus.
TL;DR: The affinity of fibronectin to cell surfaces extends to the prokaryotic cell Staphylococcus aureus, and is reported on for the first time.
Related Papers (5)
Fibronectins—adhesive glycoproteins of cell surface and blood
Kenneth M. Yamada,Kenneth Olden +1 more
Fibronectin: current concepts of its structure and functions.
Binding of soluble form of fibroblast surface protein, fibronectin, to collagen.
Eva Engvall,Erkki Ruoslahti +1 more