The Toxin–Antidote Model of Cytoplasmic Incompatibility: Genetics and Evolutionary Implications
John F. Beckmann,Manon Bonneau,Hongli Chen,Mark Hochstrasser,Denis Poinsot,Hervé Merçot,Mylène Weill,Mathieu Sicard,Sylvain Charlat +8 more
TLDR
The tight association of the CI genes with prophages provides clues to the possible evolutionary origin of this phenomenon and the levels of selection at play.About:
This article is published in Trends in Genetics.The article was published on 2019-01-23 and is currently open access. It has received 95 citations till now. The article focuses on the topics: Cytoplasmic incompatibility.read more
Citations
More filters
Journal Article
Restriction-modification systems as genomic parasites in competition for specific sequences along dna
TL;DR: In this paper, it was shown that the EcoRI restriction endonuclease-modification methylase (rm) gene pair stabilizes plasmids that carry it and that this stabilization is blocked by an RM of the same sequence specificity (EcoRI or its isoschizomer, Rsr I) but not by another RM of a different specificity (PaeR7I) on another plasmid.
Journal ArticleDOI
The Wolbachia Endosymbionts
TL;DR: The Wolbachia endosymbionts encompass a large group of intracellular bacteria of biomedical and veterinary relevance, closely related to Anaplasma, Ehrlichia, and Rickettsia, which are essential to the survival and reproduction of their filarial nematode hosts and an attractive target to fight filariasis.
Journal ArticleDOI
Two-By-One model of cytoplasmic incompatibility: Synthetic recapitulation by transgenic expression of cifA and cifB in Drosophila.
TL;DR: The Two-by-One model in wMel-infected D. melanogaster is explicitly validated, established a robust system for transgenic studies of CI in a model system, and represents the first case of completely engineering male and female animal reproduction to depend upon bacteriophage gene products.
Journal ArticleDOI
Symbiont-mediated cytoplasmic incompatibility: what have we learned in 50 years?
TL;DR: This review serves as a gateway to experimental, conceptual, and quantitative themes of CI and outlines significant gaps in understanding CI’s mechanism that are ripe for investigation from diverse subdisciplines in the life sciences.
Journal ArticleDOI
A Wolbachia nuclease and its binding partner provide a distinct mechanism for cytoplasmic incompatibility.
TL;DR: It is shown that the Wolbachia cin operon constitutes another toxin–antidote system in which CinB is a nuclease toxin and CinA binds tightly to CInB and can rescue embryo viability, providing important insights into the molecular basis of CI.
References
More filters
Journal ArticleDOI
Wolbachia: master manipulators of invertebrate biology.
TL;DR: The basic biology of Wolbachia is reviewed, with emphasis on recent advances in the authors' understanding of these fascinating endosymbionts, which are found in arthropods and nematodes.
Journal ArticleDOI
Biology of wolbachia
TL;DR: Wolbachia biology is reviewed, including their phylogeny and distribution, mechanisms of action, population biology and evolution, and biological control implications.
Journal ArticleDOI
A Wolbachia Symbiont in Aedes aegypti Limits Infection with Dengue, Chikungunya, and Plasmodium
Luciano Andrade Moreira,Inaki Iturbe-Ormaetxe,Jason A. L. Jeffery,Guangjin Lu,Alyssa T. Pyke,Lauren M. Hedges,Bruno Coelho Rocha,Sonja Hall-Mendelin,Andrew Day,Markus Riegler,Leon E. Hugo,Karyn N. Johnson,Brian H. Kay,Elizabeth A. McGraw,Andrew F. van den Hurk,Andrew F. van den Hurk,Peter A. Ryan,Scott Leslie O'Neill +17 more
TL;DR: It is suggested that this Wolbachia-mediated pathogen interference may work synergistically with the life-shortening strategy proposed previously to provide a powerful approach for the control of insect transmitted diseases.
Journal ArticleDOI
The bacterial symbiont Wolbachia induces resistance to RNA viral infections in Drosophila melanogaster.
TL;DR: It is reported that a bacterial infection renders D. melanogaster more resistant to Drosophila C virus, reducing the load of viruses in infected flies and identifying these resistance-inducing bacteria as Wolbachia.