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The underappreciated role of muscle in health and disease

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TLDR
It is imperative that factors directly related to muscle mass, strength, and metabolic function be included in future studies designed to demonstrate optimal lifestyle behaviors throughout the life span, including physical activity and diet.
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This article is published in The American Journal of Clinical Nutrition.The article was published on 2006-09-01 and is currently open access. It has received 1197 citations till now.

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Physical fitness in childhood and adolescence: a powerful marker of health

TL;DR: In this paper, a review of the latest developments with regard to physical fitness and several health outcomes in young people is presented, and the authors suggest that health promotion policies and physical activity programs should be designed to improve cardiorespiratory fitness, but also two other physical fitness components such us muscular fitness and speed/agility.
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Sarcopenia as a determinant of chemotherapy toxicity and time to tumor progression in metastatic breast cancer patients receiving capecitabine treatment.

TL;DR: Sarcopenia is a significant predictor of toxicity and TTP in metastatic breast cancer patients treated with capecitabine, and the potential use of body composition assessment to predict toxicity and individualize chemotherapy dosing is raised.
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Skeletal Muscle: A Brief Review of Structure and Function

TL;DR: This review discusses the various domains of muscle structure and function including its cytoskeletal architecture, excitation-contraction coupling, energy metabolism, and force and power generation.
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Dietary protein recommendations and the prevention of sarcopenia.

TL;DR: Clinicians should stress the importance of ingesting a sufficient amount of protein with each meal to preserve skeletal muscle mass in ageing and propose a novel and specific dietary approach to prevent or slow down muscle loss with ageing.
Journal ArticleDOI

Association between muscular strength and mortality in men: prospective cohort study

TL;DR: Muscular strength is inversely and independently associated with death from all causes and cancer in men, even after adjusting for cardiorespiratory fitness and other potential confounders.
References
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Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp.

TL;DR: A novel estimate of insulin sensitivity that is simple to calculate and provides a reasonable approximation of whole-body insulin sensitivity from the oral glucose tolerance test (OGTT).
Journal ArticleDOI

Exercise training and nutritional supplementation for physical frailty in very elderly people

TL;DR: High-intensity resistance exercise training is a feasible and effective means of counteracting muscle weakness and physical frailty in very elderly people, in contrast to multi-nutrient supplementation without concomitant exercise, which does not reduce muscle weakness orPhysical frailty.
Related Papers (5)
Trending Questions (3)
What are the main functions of involuntary muscles?

The provided paper does not mention anything about the functions of involuntary muscles. The paper focuses on the role of muscle in whole-body protein metabolism and its impact on health and disease.

How does muscle mass improve life span?

The paper does not specifically mention how muscle mass improves lifespan. The paper discusses the importance of muscle in protein metabolism and its role in preventing chronic diseases, but it does not directly address the relationship between muscle mass and lifespan.

What is the role of the muscular system in the body?

The muscular system plays a central role in whole-body protein metabolism and provides hepatic gluconeogenic precursors.