scispace - formally typeset
Open AccessJournal ArticleDOI

Traveling plateaus for a hyperbolic Keller-Segel system with attraction and repulsion: existence and branching instabilities

Reads0
Chats0
TLDR
In this paper, the authors studied the branching instability in the hyperbolic Keller-Segel system with logistic sensitivity, where repulsive and attractive forces, acting on a conservative system, create stable traveling patterns or branching instabilities.
Abstract
How can repulsive and attractive forces, acting on a conservative system, create stable traveling patterns or branching instabilities? We have proposed to study this question in the framework of the hyperbolic Keller-Segel system with logistic sensitivity. This is a model system motivated by experiments on cell communities auto-organization, a field which is also called socio-biology. We continue earlier modeling work, where we have shown numerically that branching patterns arise for this system and we have analyzed this instability by formal asymptotics for small diffusivity of the chemo-repellent. Here we are interested in the more general situation, where the diffusivities of both the chemo-attractant and the chemo-repellent are positive. To do so, we develop an appropriate functional analysis framework. We apply our method to two cases. Firstly we analyze steady states. Secondly we analyze traveling waves when neglecting the degradation coefficient of the chemo-repellent; the unique wave speed appears through a singularity cancelation which is the main theoretical difficulty. This shows that in different situations the cell density takes the shape of a plateau. The existence of steady states and traveling plateaus are a symptom of how rich the system is and why branching instabilities can occur. Numerical tests show that large plateaus may split into smaller ones, which remain stable.

read more

Citations
More filters
Journal ArticleDOI

Competing effects of attraction vs. repulsion in chemotaxis

TL;DR: In this paper, the authors considered the attraction-repulsion chemotaxis system under homogeneous Neumann boundary conditions in a bounded domain with smooth boundary and proved that the system with τ = 0 is globally well-posed in high dimensions if repulsion prevails over attraction.
Journal ArticleDOI

On the asymptotic theory from microscopic to macroscopic growing tissue models: an overview with perspectives

TL;DR: A review and critical analysis of the asymptotic limit methods focused on the derivation of macroscopic equations for a class of equations modeling complex multicellular systems by methods of the kinetic theory for active particles is presented in this article.
Journal ArticleDOI

Boundedness, blowup and critical mass phenomenon in competing chemotaxis

TL;DR: In this paper, the authors considered the Keller-Segel system and established the global existence of uniformly in-time bounded classical solutions with large initial data if the repulsion dominates or cancels attraction (i.e., ξ γ ≥ α χ ).
Journal ArticleDOI

Pattern Formation of the Attraction-Repulsion Keller-Segel System

TL;DR: In this article, the authors studied the pattern formation of the attraction-repulsion Keller-Segel (ARKS) system and established the existence of time-periodic patterns and steady state patterns for the ARKS model in the full parameter regimes.
Journal ArticleDOI

Boundedness of the attraction–repulsion Keller–Segel system

TL;DR: In this article, the authors considered the initial-boundary value problem of the attraction-repulsion Keller-Segel model describing aggregation of Microglia in the central nervous system in Alzheimer's disease due to the interaction of chemoattractant and chemorepellent.
References
More filters
Journal ArticleDOI

Development and applications of a model for cellular response to multiple chemotactic cues.

TL;DR: It is demonstrated that the model derived can generate the complex patterns observed on the skin of certain animal species and it is indicated how the chemotactic response can be viewed as a form of positional indicator.
Journal ArticleDOI

The keller-segel model with logistic sensitivity function and small diffusivity

TL;DR: Numerical and analytic evidence indicates that solutions of this problem converge to irregular patterns of cell aggregates separated by entropic shocks from vacuum regions as time tends to infinity.
Journal ArticleDOI

Branched swarming patterns on a synthetic medium formed by wild-type Bacillus subtilis strain 3610: detection of different cellular morphologies and constellations of cells as the complex architecture develops.

TL;DR: A detailed microscopic in situ analysis of swarms 1 and 2 revealed varied cell morphologies and a remarkable series of events, with cells assembling into different 'structures', as the architecture of the swarm developed.
Journal ArticleDOI

Existence of solutions of the hyperbolic Keller-Segel model

TL;DR: In this paper, the authors considered the hyperbolic Keller-Segel model with quorum sensing, a model describing the collective cell movement due to chemical signalling with a flux limitation for high cell densities.
Posted Content

Existence of solutions of the hyperbolic Keller-Segel model

TL;DR: In this paper, the authors considered the hyperbolic Keller-Segel model with quorum sensing, a model describing the collective cell movement due to chemical signalling with a flux limitation for high cell densities.
Related Papers (5)