Journal ArticleDOI
Treatment and prognosis of mature T-cell and NK-cell lymphoma: an analysis of patients with T-cell lymphoma treated in studies of the German High-Grade Non-Hodgkin Lymphoma Study Group.
Norbert Schmitz,Lorenz Trümper,Marita Ziepert,Maike Nickelsen,Anthony D. Ho,Bernd Metzner,Norma Peter,Markus Loeffler,Andreas Rosenwald,Michael Pfreundschuh +9 more
TLDR
Patients with ALK-negative ALCL, PTCLU, or AITL presenting with IPI > 1 have a poor prognosis and should be considered candidates for novel treatment strategies.About:
This article is published in Blood.The article was published on 2010-11-04. It has received 475 citations till now. The article focuses on the topics: T-cell lymphoma & International Prognostic Index.read more
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Brentuximab vedotin with chemotherapy for CD30-positive peripheral T-cell lymphoma (ECHELON-2): a global, double-blind, randomised, phase 3 trial
Steven M. Horwitz,Owen A. O'Connor,Barbara Pro,Timothy M Illidge,Michelle A. Fanale,Ranjana H. Advani,Nancy L. Bartlett,Jacob Haaber Christensen,Franck Morschhauser,Eva Domingo-Domenech,Giuseppe Rossi,Won Seog Kim,Tatyana Feldman,Anne Lennard,David Belada,Árpád Illés,Kensei Tobinai,Kunihiro Tsukasaki,Su-Peng Yeh,Andrei R. Shustov,Andreas Hüttmann,Kerry J. Savage,Sam Yuen,Swaminathan Padmanabhan Iyer,Pier Luigi Zinzani,Zhaowei Hua,Meredith Little,Shangbang Rao,Joseph Woolery,Thomas Manley,Lorenz Trümper +30 more
TL;DR: Front-line treatment with A+CHP is superior to CHOP for patients with CD30-positive peripheral T-cell lymphomas as shown by a significant improvement in progression-free survival and overall survival with a manageable safety profile.
Journal ArticleDOI
Up-Front Autologous Stem-Cell Transplantation in Peripheral T-Cell Lymphoma: NLG-T-01
Francesco d'Amore,Thomas Relander,Grete F. Lauritzsen,Esa Jantunen,Hans Hagberg,Harald Anderson,Harald Holte,Anders Österborg,Mats Merup,Peter de Nully Brown,Outi Kuittinen,Martin Erlanson,Bjørn Østenstad,Unn-Merete Fagerli,Ole V. Gadeberg,Christer Sundström,Jan Delabie,Elisabeth Ralfkiaer,Martine Vornanen,Helle Toldbod +19 more
TL;DR: Dose-dense induction followed by HDT/ASCT was well tolerated and led to long-term PFS in 44% of treatment-naive patients with PTCL, which represents an encouraging outcome, particularly considering the high median age and adverse risk profile of the study population.
Journal ArticleDOI
Chimeric antigen receptor T-cell therapies for lymphoma
TL;DR: Clinical efficacy and toxicity of CAR-T-cell therapies for lymphoma are reviewed, and their limitations and future directions with regard to toxicity management, CAR designs and CAR- t cells phenotypes, conditioning regimens, and combination therapies are discussed.
Journal ArticleDOI
ESMO Consensus conferences: guidelines on malignant lymphoma. part 2: marginal zone lymphoma, mantle cell lymphoma, peripheral T-cell lymphoma
Martin Dreyling,Catherine Thieblemont,Andrea Gallamini,Luca Arcaini,Elias Campo,Olivier Hermine,Johanna Kluin-Nelemans,Marco Ladetto,S. Le Gouill,E. Iannitto,S. A. Pileri,J. Rodriguez,Norbert Schmitz,Andrew Wotherspoon,Pier Luigi Zinzani,Emanuele Zucca +15 more
TL;DR: This consensus report focuses on the three less common lymphoproliferative malignancies: marginal zone lymphoma, mantle cell lymphomas, and peripheral T-cell lymphomas.
Journal ArticleDOI
Real world data on prognostic factors and treatment in peripheral T-cell lymphomas: a study from the Swedish Lymphoma Registry
TL;DR: This study is the largest population-based P TCL cohort reported so far and provides important information on outcome in PTCL outside the setting of clinical trials.
References
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Book
WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues
TL;DR: Thank you very much for reading who classification of tumours of haematopoietic and lymphoid tissues, and maybe you have knowledge that, people have look hundreds of times for their chosen readings like this, but end up in malicious downloads.
Journal ArticleDOI
CHOP Chemotherapy plus Rituximab Compared with CHOP Alone in Elderly Patients with Diffuse Large-B-Cell Lymphoma
Bertrand Coiffier,Eric Lepage,Josette Brière,Raoul Herbrecht,Hervé Tilly,Reda Bouabdallah,Pierre Morel,Eric Van Den Neste,Gilles Salles,Philippe Gaulard,Felix Reyes,Pierre Lederlin,Christian Gisselbrecht +12 more
TL;DR: A randomized trial to compare CHOP chemotherapy plus rituximab with CHOP alone in elderly patients with diffuse large-B-cell lymphoma found the rate of complete response was significantly higher in the group that received CHOP plus r ituximabs than in thegroup that receivedCHOP alone.
Journal ArticleDOI
E.S. Jaffe, N.L. Harris, H. Stein, J.W. Vardiman (eds). World Health Organization Classification of Tumours: Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues
Journal Article
A predictive model for aggressive non-Hodgkin's lymphoma
Margaret A. Shipp,D. P. Harrington,James R. Anderson,James Olen Armitage,Gianni Bonadonna,G. Brittinger,Fernando Cabanillas,George P. Canellos,Bertrand Coiffier,Joseph M. Connors,R. A. Cowan,D. Crowther,Steve Dahlberg,M. Engelhard,Richard I. Fisher,Christian Gisselbrecht,Sandra J. Horning,Eric Lepage,T. A. Lister,J. H. Meerwaldt,Emili Montserrat,Nis I. Nissen,M. M. Oken,Bruce A. Peterson,Carlo Tondini,W. A. Velasquez,B. Y. Yeap +26 more
TL;DR: The international index and the age-adjusted international index should be used in the design of future therapeutic trials in patients with aggressive non-Hodgkin's lymphoma and in the selection of appropriate therapeutic approaches for individual patients.
Journal ArticleDOI
International peripheral T-cell and natural killer/T-cell lymphoma study: pathology findings and clinical outcomes.
TL;DR: The use of an anthracycline-containing regimen was not associated with an improved outcome in PTCL-NOS or angioimmunoblastic type, but was associated with a better outcome in anaplastic large-cell lymphoma, ALK positive.
Related Papers (5)
International peripheral T-cell and natural killer/T-cell lymphoma study: pathology findings and clinical outcomes.
Up-Front Autologous Stem-Cell Transplantation in Peripheral T-Cell Lymphoma: NLG-T-01
Francesco d'Amore,Thomas Relander,Grete F. Lauritzsen,Esa Jantunen,Hans Hagberg,Harald Anderson,Harald Holte,Anders Österborg,Mats Merup,Peter de Nully Brown,Outi Kuittinen,Martin Erlanson,Bjørn Østenstad,Unn-Merete Fagerli,Ole V. Gadeberg,Christer Sundström,Jan Delabie,Elisabeth Ralfkiaer,Martine Vornanen,Helle Toldbod +19 more
Pralatrexate in Patients With Relapsed or Refractory Peripheral T-Cell Lymphoma: Results From the Pivotal PROPEL Study
Owen A. O'Connor,Barbara Pro,Lauren Pinter-Brown,Nancy L. Bartlett,Leslie Popplewell,Bertrand Coiffier,Mary Jo Lechowicz,Kerry J. Savage,Andrei R. Shustov,Christian Gisselbrecht,Eric D. Jacobsen,Pier Luigi Zinzani,Richard R. Furman,Andre Goy,Corinne Haioun,Michael Crump,Jasmine Zain,Eric D. Hsi,Adam P. Boyd,Steven M. Horwitz +19 more