Journal ArticleDOI
Ulosantoin, a potent insecticide from the sponge Ulosa ruetzleri
Bradford C. Vanwagenen,Raymond D. Larsen,John H. Cardellina,David Randazzo,Zev Lidert,Colin Swithenbank +5 more
TLDR
A phosphorylated hydantoin has been isolated from organic soluble extracts of the sponge Ulosa ruetzleri and found to exhibit marked insecticidal activity against tobacco hornworm larvae and cockroaches.Abstract:
Ulosantoin (2), a phosphorylated hydantoin, has been isolated from organic soluble extracts of the sponge Ulosa ruetzleri and found to exhibit marked insecticidal activity against tobacco hornworm larvae and cockroaches. The structure was determined by X-ray diffraction analysis. A structurally related compound, dimethyl N 2 -creatininylphosphate (1), was also isolated from the sponge extracts, but was inactive in the insecticidal screensread more
Citations
More filters
Journal ArticleDOI
Review of human butyrylcholinesterase structure, function, genetic variants, history of use in the clinic, and potential therapeutic uses.
TL;DR: Gene therapy with a vector that sustains expression for a year from a single injection is a promising method for delivering therapeutic quantities of BChE.
Journal ArticleDOI
Natural products inhibitors of the enzyme acetylcholinesterase
José Maria Barbosa Filho,Karina Carla de Paula Medeiros,Margareth de Fátima Formiga Melo Diniz,Leônia Maria Batista,Petrônio Filgueiras de Athayde-Filho,Marcelo Sobral da Silva,Emídio Vasconcelos Leitão da Cunha,Jackson Roberto Guedes da Silva Almeida,Lucindo José Quintans-Júnior +8 more
TL;DR: The present work reviews the literature on plants and plant-derived compounds inhibitors of enzyme acetylcholinesterase and refers to 309 plant extracts and 260 compounds isolated from plants, which are classified in appropriate chemical groups and model tested, and cites their activity.
Journal ArticleDOI
Natural products, their derivatives, mimics and synthetic equivalents: role in agrochemical discovery
TL;DR: The overall impact of NPs to the discovery of herbicides has been relatively modest compared to the impact observed for fungicides and insecticides, however, as new sourcing and approaches to NP discovery evolve, the impact ofNPs in all agrochemical arenas will continue to expand.
Journal ArticleDOI
Solution structure by NMR of circulin A: a macrocyclic knotted peptide having anti-HIV activity
Norelle L. Daly,Anita Koltay,Kirk R. Gustafson,Michael R. Boyd,José R. Casas-Finet,David J. Craik +5 more
TL;DR: The three-dimensional solution structure of circulin A, a 30 residue polypeptide from the African plant Chassalia parvifolia, has been determined using two-dimensional 1H-NMR spectroscopy and provides additional evidence for a solvent-exposed Trp residue.
Journal ArticleDOI
Estimation of total phenol and in vitro antioxidant activity of Albizia procera leaves
Mahfuza khatoon,Ekramul Islam,Rafikul Islam,Aziz Abdur Rahman,Ahm Khurshid Alam,Proma Khondkar,Mamunur Rashid,Shahnaj Parvin +7 more
TL;DR: The above evidences suggest that APE of A. procera leaf is a potential source of natural antioxidant and can be used to prevent diseases associated with free radicals.