Ultra-Processed Food Consumption and Mental Health: A Systematic Review and Meta-Analysis of Observational Studies
Melissa Lane,E. Gamage,Nikolaj Travica,Thusharika Dissanayaka,Deborah N Ashtree,Sarah Megan Gauci,Mojtaba Lotfaliany,Adrienne O'Neil,Felice N. Jacka,Wolfgang Marx +9 more
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TLDR
Evidence is found for associations between ultra-processed food consumption and adverse mental health, and further rigorously designed prospective and experimental studies are needed to better understand causal pathways.Abstract:
Since previous meta-analyses, which were limited only to depression and by a small number of studies available for inclusion at the time of publication, several additional studies have been published assessing the link between ultra-processed food consumption and depression as well as other mental disorders. We aimed to build on previously conducted reviews to synthesise and meta-analyse the contemporary evidence base and clarify the associations between the consumption of ultra-processed food and mental disorders. A total of 17 observational studies were included (n = 385,541); 15 cross-sectional and 2 prospective. Greater ultra-processed food consumption was cross-sectionally associated with increased odds of depressive and anxiety symptoms, both when these outcomes were assessed together (common mental disorder symptoms odds ratio: 1.53, 95%CI 1.43 to 1.63) as well as separately (depressive symptoms odds ratio: 1.44, 95%CI 1.14 to 1.82; and, anxiety symptoms odds ratio: 1.48, 95%CI 1.37 to 1.59). Furthermore, a meta-analysis of prospective studies demonstrated that greater ultra-processed food intake was associated with increased risk of subsequent depression (hazard ratio: 1.22, 95%CI 1.16 to 1.28). While we found evidence for associations between ultra-processed food consumption and adverse mental health, further rigorously designed prospective and experimental studies are needed to better understand causal pathways.read more
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Higher Ultra-Processed Food Consumption Is Associated with Greater High-Sensitivity C-Reactive Protein Concentration in Adults: Cross-Sectional Results from the Melbourne Collaborative Cohort Study
Melissa Lane,Mojtaba Lotfaliany,Malcolm Forbes,Amy Loughman,Tetyana Rocks,Adrienne O'Neil,Priscila Pereira Machado,Felice N. Jacka,Allison M. Hodge,Wolfgang Marx +9 more
TL;DR: Higher ultra-processed food intake was cross-sectionally associated with elevated hsCRP, which appeared to occur independent of body mass index.
Journal ArticleDOI
Ultra-Processed Food Consumption and Depressive Symptoms in a Mediterranean Cohort
Justyna Godos,Marialaura Bonaccio,Wahidah H. Al-Qahtani,Wolfgang Marx,Melissa Lane,Gian Marco Leggio,Giuseppe Grosso +6 more
TL;DR: In this article , the authors investigated the relationship between consumption of ultra-processed foods and depressive symptoms in a sample of younger Italian adults, and found that individuals in the highest quartile of UPF consumption had higher odds of having depressive symptoms.
Journal ArticleDOI
Low-Grade Inflammation and Ultra-Processed Foods Consumption: A Review
TL;DR: In this article , the authors summarize the available evidence on the possible relationship between excessive consumption of ultra-processed foods and modulation of low-grade inflammation, as potential promoters of chronic disease.
Journal ArticleDOI
Increased Consumption of Ultra-Processed Food Is Associated with Poor Mental Health in a Nationally Representative Sample of Adolescent Students in Brazil
Arthur Eumann Mesas,Alberto Durán González,Selma Maffei de Andrade,Vicente Martínez-Vizcaíno,José Francisco López-Gil,Estela Jiménez-López +5 more
TL;DR: In this paper , the authors analyzed the association between ultra-processed food consumption and mental health symptoms in a nationally representative sample of the Brazilian adolescent student population and concluded that the higher the consumption of UPF, the higher frequency of reported symptoms of poor mental health.
Posted ContentDOI
GroceryDB: Prevalence of Processed Food in Grocery Stores
TL;DR: It is shown that there is no single nutrient or ingredient "bio-marker" for ultra-processed food, allowing us to quantify the individual contribution of over 1,000 ingredients to ultra-processing.
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