Open Access
Updating the Theory of Mutation
John W. Drake,Barry W. Glickman,Lynn S. Ripley +2 more
- Vol. 71, Iss: 6, pp 621-630
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The article was published on 1983-11-01 and is currently open access. It has received 49 citations till now. The article focuses on the topics: Mutation (genetic algorithm).read more
Citations
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Novel recombinations in the maize mitochondrial genome produce a unique transcriptional unit in the Texas male-sterile cytoplasm.
TL;DR: A 3547 bp DNA fragment from male-sterile maize mitochondria, designated TURF 2H3, selected because of its unique and abundant transcripts appears to be uniquely altered in cms-T plants restored to fertility by the nuclear restorer genes Rf1 and Rf2.
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Microsatellite polymorphism in natural populations of the wild plant Arabidopsis thaliana.
TL;DR: Variation in repeat number at 20 microsatellite loci of Arabidopsis thaliana was studied in a worldwide sample of 42 ecotypes to investigate the pattern and level of polymorphism in repetitive sequences in natural plant populations.
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Patterns of Somatic Mutations in Immunoglobulin Variable Genes
TL;DR: Although additional factors may be involved in targeting mutations to the variable gene, mistemplating by nearby repeats may provide a mechanism for the enhancement of somatic mutation.
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The tobacco mitochondrial ATPase subunit 9 gene is closely linked to an open reading frame for a ribosomal protein
TL;DR: The distribution and orientation of the S13-like and “URF 1”-like sequences are discussed and the possibility that they are active genes is discussed.
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On the deletion of inverted repeated DNA in Escherichia coli: effects of length, thermal stability, and cruciform formation in vivo.
TL;DR: A kinetic model is presented to describe the relationship between the physical-chemical properties of DNA structure and the deletion of inverted repeats in living cells and it is demonstrated that length, thermal stability of base pairing in the hairpin stem, and ease of cruciform formation affect the frequency of deletion.
References
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Ultraviolet mutagenesis and inducible DNA repair in Escherichia coli.
TL;DR: This work states that the "SOS" Hypothesis, the Regulatory Role of DNA Damage in E. coli, and the Mechanism of SOS Repair in Bacteria and other UV-INDUCIBLE FUNCTIONS, and Regulations of SOS REPAIR, are valid hypotheses for the regulation of SOS functions.
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The structure of dna
James D. Watson,Francis Crick +1 more
TL;DR: The detailed structure described by Crick and Watson has been shown to have too large a diameter, and a drawing has been given of an improved model which is in fairly good agreement with the s-ray data.
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Possible Relevance of O–6 Alkylation of Deoxyguanosine to the Mutagenicity and Carcinogenicity of Nitrosamines and Nitrosamides
TL;DR: Genetic studies of alkylation mutants in bacteria and bacteriophages have shown that many point mutational events involve guanine to adenine transitions, and the most abundant reaction product found in acid hydrolysates of treated DNA is 7-alkyl Guanine.
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DNA Repair Enzymes
TL;DR: The present invention relates to the methods of selecting compounds which modulate the activity of DNA repair enzymes HAB1 and HAB2 and their uses in the treatment of disorders, which would benefit from an increase or a decrease in HAB 1 or HAB 2 activity.
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Enzymatic synthesis of deoxyribonucleic acid. xiv. further purification and properties of deoxyribonucleic acid polymerase of escherichia coli.
TL;DR: Exonuclease function of DNA polymerase from Escherichia colis, discussing hydrolysis of polydeoxyribonucleotides and resistancy of oligonucleotide.