Urinary Concentrations of Organophosphate Flame Retardant Metabolites and Pregnancy Outcomes among Women Undergoing in Vitro Fertilization
Courtney C. Carignan,Lidia Mínguez-Alarcón,Craig M. Butt,Paige L. Williams,John D. Meeker,Heather M. Stapleton,Thomas L. Toth,Jennifer B. Ford,Russ Hauser +8 more
Reads0
Chats0
TLDR
Using IVF to investigate human reproduction and pregnancy outcomes, it was found that concentrations of some urinary PFR metabolites were negatively associated with proportions of successful fertilization, implantation, clinical pregnancy, and live birth.Abstract:
Background: Evidence from animal studies suggests that exposure to organophosphate flame retardants (PFRs) can disrupt endocrine function and impair embryo development. However, no epidemiologic st...read more
Citations
More filters
Journal ArticleDOI
Organophosphate Ester Flame Retardants: Are They a Regrettable Substitution for Polybrominated Diphenyl Ethers?
Arlene Blum,Mamta Behl,Linda S. Birnbaum,Miriam L. Diamond,Allison L. Phillips,Veena Singla,Nisha S. Sipes,Heather M. Stapleton,Marta Venier +8 more
TL;DR: Given the large number of OPFRs in use, manufacturers can move towards healthier and safer products by developing innovative ways to reduce fire hazard for electronics enclosures, upholstered furniture, building materials and other consumer products without adding flame retardant chemicals.
Journal ArticleDOI
Partition and source identification of organophosphate esters in the water and sediment of Taihu Lake, China
TL;DR: Principal component analysis indicated that OPE manufacturing in Yixing was an important point source of OPEs, especially of TCIPP in Taihu Lake, and their partitioning behaviors between sediment and water was dominated by hydrophobic interaction.
Journal ArticleDOI
Paternal urinary concentrations of organophosphate flame retardant metabolites, fertility measures, and pregnancy outcomes among couples undergoing in vitro fertilization.
Courtney C. Carignan,Courtney C. Carignan,Lidia Mínguez-Alarcón,Paige L. Williams,John D. Meeker,Heather M. Stapleton,Craig M. Butt,Thomas L. Toth,Jennifer B. Ford,Russ Hauser,Earth Study Team +10 more
TL;DR: Using IVF as a model to investigate human reproduction and pregnancy outcomes, it was found that paternal urinary concentrations of BDCIPP were associated with reduced fertilization and female preconception exposure to ΣPFRs may be more relevant to adverse pregnancy outcomes.
Journal ArticleDOI
Biomarkers, matrices and analytical methods targeting human exposure to chemicals selected for a European human biomonitoring initiative
Katrin Vorkamp,Argelia Castaño,Jean-Philippe Antignac,Luis D. Boada,Enrique Cequier,Adrian Covaci,Marta Esteban López,Line Småstuen Haug,Monika Kasper-Sonnenberg,Holger M. Koch,Octavio P. Luzardo,Agnese Osīte,Loïc Rambaud,Maria-Teresa Pinorini,Gabriele Sabbioni,Cathrine Thomsen +15 more
TL;DR: High performance liquid chromatography-tandem mass spectrometry (LC-MS/MS) was the method of choice for bisphenols, PFASs, the HFR hexabromocyclodododecane (HBCDD), phenolic HFRs as well as the metabolites of phthalates, DINCH, OPFRs and PAHs in urine.
Journal ArticleDOI
Characterization of Individual Isopropylated and tert-Butylated Triarylphosphate (ITP and TBPP) Isomers in Several Commercial Flame Retardant Mixtures and House Dust Standard Reference Material SRM 2585.
TL;DR: In this paper, the authors quantified the contribution of individual ITP and TBPP isomers in four commercial flame retardant mixtures: FM 550, FM 600, an ITP mixture, and a TBPP mixture.
References
More filters
Journal ArticleDOI
Estimation of Average Concentration in the Presence of Nondetectable Values
TL;DR: In this article, the average concentration of a particular contaminant during some period of time, a certain proportion of the collected samples is often reported to be below the limit of detection.
Journal ArticleDOI
Phosphorus flame retardants: Properties, production, environmental occurrence, toxicity and analysis
Ike van der Veen,Jacob de Boer +1 more
TL;DR: In this paper, the use of PFRs as potential substitutes for brominated flame retardants (BFRs) has been discussed and a number of potential alternatives for BFRs have been proposed.
Fertility, family planning, and reproductive health of U.S. Women: Data from the 2002 national survey of family growth
TL;DR: National estimates of fertility, family planning, and reproductive health indicators among females 15-44 years of age in the United States in 2002 from Cycle 6 of the National Survey of Family Growth (NSFG).
Journal ArticleDOI
Detection of organophosphate flame retardants in furniture foam and U.S. house dust.
Heather M. Stapleton,Susan L. Klosterhaus,Sarah Eagle,Jennifer Fuh,John D. Meeker,Arlene Blum,Thomas F. Webster +6 more
TL;DR: This paper analyzed foam samples from 26 different pieces of furniture purchased in the United States primarily between 2003 and 2009, including couches, chairs, mattress pads, pillows, and in one case, foam from a sound-proofing system of a laboratory-grade dust sieve.
Journal ArticleDOI
Prevalence of infertility in the United States as estimated by the current duration approach and a traditional constructed approach.
Marie E. Thoma,Alexander C. McLain,Jean Fredo Louis,Rosalind B. King,Ann Trumble,Rajeshwari Sundaram,Germaine M. Buck Louis +6 more
TL;DR: Infertility prevalence based on a current duration approach was consistent with other US prospective cohort studies with preconception enrollment, and underscores the importance of definition and methodologic approach for estimating the prevalence of infertility.
Related Papers (5)
Phosphorus flame retardants: Properties, production, environmental occurrence, toxicity and analysis
Ike van der Veen,Jacob de Boer +1 more