Journal ArticleDOI
Vitamin D and metabolic health with special reference to the effect of vitamin D on serum lipids
Rolf Jorde,Guri Grimnes +1 more
TLDR
Considering the numerous other promising vitamins and minerals that when properly tested have been disappointing, one should wait for the results of forthcoming vitamin D intervention studies before drawing conclusions on potential beneficial effects of vitamin D.About:
This article is published in Progress in Lipid Research.The article was published on 2011-10-01. It has received 308 citations till now. The article focuses on the topics: Vitamin D and neurology & Calcitriol receptor.read more
Citations
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Journal ArticleDOI
Vitamin D and Cardiovascular Disease
Paul Norman,Janet T. Powell +1 more
TL;DR: This review summarizes the clinical studies showing associations between vitamin D status and cardiovascular disease and the experimental studies that explore the mechanistic basis for these associations.
Journal ArticleDOI
Obesity and dyslipidemia.
Jelena Vekic,Aleksandra Zeljkovic,Aleksandra Stefanović,Zorana Jelic-Ivanovic,Vesna Spasojevic-Kalimanovska +4 more
TL;DR: This review will address the main characteristics of dyslipidemia and mechanisms that induce its development in obesity, in particular proprotein convertase subtilisin/kexin type 9 (PCSK9), as the key molecule that regulates metabolism of low-density lipoproteins (LDL), and sphingosine-1-phosphate (S1P), as one of the most important mediators of high-densitylipoprotein (HDL) particles function.
Journal ArticleDOI
Vitamin D and cardiovascular disease prevention
Stefan Pilz,Nicolas Verheyen,Martin R. Grübler,Martin R. Grübler,Andreas Tomaschitz,Winfried März +5 more
TL;DR: Current available evidence does not support cardiovascular benefits or harms of vitamin D supplementation with the commonly used doses, and whether vitamin D has cardiovascular effects in individuals with overt vitamin D deficiency remains to be evaluated.
Journal ArticleDOI
Influence of vitamin D supplementation on plasma lipid profiles: A meta-analysis of randomized controlled trials
TL;DR: The lipid modulating effects of vitamin D supplementation should be further investigated though large-scale, randomized trials with adequate doses which can effectively elevated the active form ofitamin D in plasma and with proper population which has hyperlipemia as an inclusion criterion.
Journal ArticleDOI
Vitamin D and Cardiovascular Disease: Controversy Unresolved.
Ibhar Al Mheid,Arshed A. Quyyumi +1 more
TL;DR: Meta-analyses of vitamin D supplementation trials have failed to show clear improvements in blood pressure, insulin sensitivity, or lipid parameters, thus suggesting that the link between vitamin D deficiency and cardiovascular disease may be an epiphenomenon.
References
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Journal ArticleDOI
Vitamin D Deficiency
TL;DR: The role of vitamin D in skeletal and nonskeletal health is considered and strategies for the prevention and treatment ofitamin D deficiency are suggested.
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The 2011 Report on Dietary Reference Intakes for Calcium and Vitamin D from the Institute of Medicine: What Clinicians Need to Know
A. Catharine Ross,JoAnn E. Manson,Steven A. Abrams,John F. Aloia,John F. Aloia,Patsy M. Brannon,Steven K. Clinton,Ramon Durazo-Arvizu,J. Christopher Gallagher,Richard L. Gallo,Glenville Jones,Christopher S. Kovacs,Susan Taylor Mayne,Clifford J. Rosen,Sue A. Shapses +14 more
TL;DR: The Committee concluded that the prevalence of vitamin D inadequacy in North America has been overestimated and urgent research and clinical priorities were identified, including reassessment of laboratory ranges for 25-hydroxyvitamin D, to avoid problems of both undertreatment and overtreatment.
Journal ArticleDOI
Vitamin D Deficiency and Risk of Cardiovascular Disease
Thomas J. Wang,Michael J. Pencina,Sarah L. Booth,Paul F. Jacques,Erik Ingelsson,Katherine J. Lanier,Emelia J. Benjamin,Ralph B. D'Agostino,Myles Wolf,Ramachandran S. Vasan +9 more
TL;DR: Vitamin D deficiency is associated with incident cardiovascular disease and further clinical and experimental studies may be warranted to determine whether correction of vitamin D deficiency could contribute to the prevention of cardiovascular disease.
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Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health outcomes
Heike A. Bischoff-Ferrari,Edward Giovannucci,Walter C. Willett,Thomas Dietrich,Bess Dawson-Hughes +4 more
TL;DR: Evidence from studies that evaluated thresholds for serum 25(OH)D concentrations in relation to bone mineral density, lower-extremity function, dental health, and risk of falls, fractures, and colorectal cancer suggests that an increase in the currently recommended intake of vitamin D is warranted.
Journal ArticleDOI
Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: Systematic review and meta-analysis
TL;DR: Treatment with beta carotene, vitamin A, vitamin E, and vitamin E may increase mortality and the potential roles of vitamin C and selenium on mortality need further study.