Does the Covid vaccine use synthetic RNA?
Answers from top 10 papers
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Papers (10) | Insight |
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COVID-19 vaccine efforts mark the first use of mRNA-type vaccines ever evaluated. | |
RNA, on the other hand, is readily taken up and expressed by DC, making it an alternative vaccine candidate. | |
103 Citations | Synthetic mRNA represents an exciting cancer vaccine technology to the implementation of effective cancer immunotherapy. |
15 Citations | Therefore, RNA adjuvants have broad applicability and can be used with all conventional vaccines to improve vaccine efficacy qualitatively and quantitively. |
198 Citations | We conclude that the self-replicative recombinant SFV RNA may be quite useful as a nucleic acid vaccine. |
Thus, disruption of conserved RNA secondary structures could be a novel strategy for the generation of attenuated SARS-CoV-2 vaccines for use against the current COVID-19 pandemic. | |
230 Citations | Our findings suggest that the nucleoside-modified mRNA-LNP vaccine platform can induce robust immune responses and is a promising candidate to combat COVID-19. |
17 Citations | Altogether, synthetic biology can help to develop improved vaccine candidates in considerably less time compared to conventional approaches. |
74 Citations | This demonstrates that DNA vaccine potency may be augmented by the incorporation of RIG-I-activating immunostimulatory RNA into the vector backbone. |
20 Citations | The RNA initiates limited replication of a genetically defined, live-attenuated vaccine virus in the tissues of the vaccine recipient, thereby inducing a protective immune response. |