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Adam Kepecs
Researcher at Washington University in St. Louis
Publications - 80
Citations - 9530
Adam Kepecs is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Basal forebrain & Interneuron. The author has an hindex of 36, co-authored 79 publications receiving 7506 citations. Previous affiliations of Adam Kepecs include Watson School of Biological Sciences & Hungarian Academy of Sciences.
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Cortical interneurons that specialize in disinhibitory control
Hyun Jae Pi,Balázs Hangya,Balázs Hangya,Duda Kvitsiani,Joshua I. Sanders,Z. Josh Huang,Adam Kepecs +6 more
TL;DR: A class of interneurons that express vasoactive intestinal polypeptide (VIP) mediates disinhibitory control in multiple areas of neocortex and is recruited by reinforcement signals, revealing a specific cell type and microcircuit underlying disinhibited control in cortex and demonstrating that it is activated under specific behavioural conditions.
Journal ArticleDOI
Interneuron cell types are fit to function
Adam Kepecs,Gordon Fishell +1 more
TL;DR: This perspective emphasizes that the ultimate goal is to dispense with classification criteria and directly define interneuron types by function, and views them as elaborations of a much more finite group of developmentally specified cardinal classes that become further specialized as they mature.
Journal ArticleDOI
Neural correlates, computation and behavioural impact of decision confidence
Adam Kepecs,Naoshige Uchida,Naoshige Uchida,Hatim A. Zariwala,Hatim A. Zariwala,Zachary F. Mainen,Zachary F. Mainen +6 more
TL;DR: The firing rates of many single neurons in the orbitofrontal cortex match closely to the predictions of confidence models and cannot be readily explained by alternative mechanisms, such as learning stimulus–outcome associations.
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A deep learning framework for neuroscience
Blake A. Richards,Timothy P. Lillicrap,Philippe Beaudoin,Yoshua Bengio,Yoshua Bengio,Rafal Bogacz,Amelia J. Christensen,Claudia Clopath,Rui Ponte Costa,Rui Ponte Costa,Archy O. de Berker,Surya Ganguli,Surya Ganguli,Colleen J Gillon,Danijar Hafner,Danijar Hafner,Adam Kepecs,Nikolaus Kriegeskorte,Peter E. Latham,Grace W. Lindsay,Kenneth D. Miller,Richard Naud,Christopher C. Pack,Panayiota Poirazi,Pieter R. Roelfsema,João Sacramento,Andrew M. Saxe,Benjamin Scellier,Anna C. Schapiro,Walter Senn,Greg Wayne,Daniel L. K. Yamins,Friedemann Zenke,Friedemann Zenke,Joel Zylberberg,Joel Zylberberg,Denis Therien,Konrad P. Kording,Konrad P. Kording +38 more
TL;DR: It is argued that a deep network is best understood in terms of components used to design it—objective functions, architecture and learning rules—rather than unit-by-unit computation.
Journal ArticleDOI
Distinct behavioural and network correlates of two interneuron types in prefrontal cortex
Duda Kvitsiani,Sachin P. Ranade,Balázs Hangya,Hiroki Taniguchi,Hiroki Taniguchi,Josh Huang,Adam Kepecs +6 more
TL;DR: A connection between the circuit-level function of different interneuron types in regulating the flow of information and the behavioural functions served by the cortical circuits is suggested, bolster the hope that functional response diversity during behaviour can in part be explained by cell-type diversity.