A
Africa Couto
Researcher at University of Nottingham
Publications - 9
Citations - 3993
Africa Couto is an academic researcher from University of Nottingham. The author has contributed to research in topics: Olfactory receptor & Antennal lobe. The author has an hindex of 8, co-authored 9 publications receiving 3685 citations. Previous affiliations of Africa Couto include Laboratory of Molecular Biology & Austrian Academy of Sciences.
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Journal ArticleDOI
A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila
Georg Dietzl,Doris Chen,Frank Schnorrer,Kuan-Chung Su,Yulia Barinova,Michaela Fellner,Michaela Fellner,Beate Gasser,Kaolin Kinsey,Kaolin Kinsey,Silvia Oppel,Silvia Oppel,Susanne Scheiblauer,Africa Couto,Vincent Marra,Krystyna Keleman,Krystyna Keleman,Barry J. Dickson,Barry J. Dickson +18 more
TL;DR: The generation and validation of a genome-wide library of Drosophila melanogaster RNAi transgenes, enabling the conditional inactivation of gene function in specific tissues of the intact organism and opening up the prospect of systematically analysing gene functions in any tissue and at any stage of the Drosophile lifespan.
Journal ArticleDOI
Molecular, anatomical, and functional organization of the Drosophila olfactory system
TL;DR: These Or expression and ORN connectivity maps provide further insight into the molecular, anatomical, and functional organization of the Drosophila olfactory system and provide an essential resource for investigating how internal odor representations are generated and how they are further processed and transmitted to higher brain centers.
Journal ArticleDOI
Temporal target restriction of olfactory receptor neurons by Semaphorin-1a/PlexinA-mediated axon-axon interactions.
Lora B. Sweeney,Africa Couto,Ya-Hui Chou,Daniela Berdnik,Barry J. Dickson,Liqun Luo,Takaki Komiyama +6 more
TL;DR: It is proposed that Sema-1a/PlexinA-mediated repulsion provides a mechanism by which early-arrived ORN axons constrain the target choices of late-arriving axons.
Journal ArticleDOI
Wiring Stability of the Adult Drosophila Olfactory Circuit after Lesion
TL;DR: It is concluded that, although adult olfactory neurons can undergo plastic changes in response to the loss of competition, the Olfactory circuit overall is extremely stable in preserving segregated information channels in this discrete map.
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In vivo genetic dissection of O2-evoked cGMP dynamics in a Caenorhabditis elegans gas sensor
TL;DR: It is shown that a rise in O2 can evoke a tonic increase in cGMP that requires an atypical O2-binding soluble guanylate cyclase and that is sustained until oxygen levels fall, which leads to a sustained Ca2+ response in the neuron that depends on cG MP-gated ion channels.