A
Akihiro Kondo
Researcher at Osaka University
Publications - 70
Citations - 2421
Akihiro Kondo is an academic researcher from Osaka University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 25, co-authored 55 publications receiving 2267 citations.
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Journal ArticleDOI
Comparison of the methods for profiling glycoprotein glycans--HUPO Human Disease Glycomics/Proteome Initiative multi-institutional study.
Yoshinao Wada,Parastoo Azadi,Catherine E. Costello,Anne Dell,Raymond A. Dwek,Hildegard Geyer,Rudolf Geyer,Kazuaki Kakehi,Niclas G. Karlsson,Koichi Kato,Nana Kawasaki,Kay-Hooi Khoo,Soo Hyun Kim,Akihiro Kondo,Erika Lattova,Yehia Mechref,Eiji Miyoshi,Kazuyuki Nakamura,Hisashi Narimatsu,Milos V. Novotny,Nicolle H. Packer,Hélène Perreault,Jasna Peter-Katalinić,Gottfried Pohlentz,Vernon N. Reinhold,Pauline M. Rudd,Pauline M. Rudd,Akemi Suzuki,Naoyuki Taniguchi +28 more
TL;DR: The results of this multi-institutional study indicate that MS-based analysis appears as the efficient method for identification and quantitation of oligosaccharides in glycomic studies and endorse the power of MS for glycopeptide characterization with high sensitivity in proteomic programs.
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Dysregulation of TGF-β1 receptor activation leads to abnormal lung development and emphysema-like phenotype in core fucose-deficient mice
Xiangchun Wang,Shinya Inoue,Jianguo Gu,Eiji Miyoshi,Katsuhisa Noda,Wenzhe Li,Yoko Mizuno-Horikawa,Miyako Nakano,Michio Asahi,Motoko Takahashi,Motoko Takahashi,Naofumi Uozumi,Shinji Ihara,Seung Ho Lee,Yoshitaka Ikeda,Yoshitaka Ikeda,Yukihiro Yamaguchi,Yukihiro Yamaguchi,Yoshiya Aze,Yoshiaki Tomiyama,Junichi Fujii,Junichi Fujii,Keiichiro Suzuki,Keiichiro Suzuki,Akihiro Kondo,Steven D. Shapiro,Carlos López-Otín,Tomoyuki Kuwaki,Masaru Okabe,Koichi Honke,Koichi Honke,Naoyuki Taniguchi +31 more
TL;DR: It is proposed that the lack of core fucosylation of TGF-beta1 receptors is crucial for a developmental and progressive/destructive emphysema, suggesting that perturbation of this function could underlie certain cases of human emphySEma.
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Comparison of Methods for Profiling O-Glycosylation HUMAN PROTEOME ORGANISATION HUMAN DISEASE GLYCOMICS/PROTEOME INITIATIVE MULTI-INSTITUTIONAL STUDY OF IgA1
Yoshinao Wada,Anne Dell,Stuart M. Haslam,Bérangère Tissot,Kevin Canis,Parastoo Azadi,Malin Bäckström,Catherine E. Costello,Gunnar C. Hansson,Yoshiyuki Hiki,Mayumi Ishihara,Hiromi Ito,Kazuaki Kakehi,Niclas G. Karlsson,Catherine A. Hayes,Koichi Kato,Koichi Kato,Nana Kawasaki,Kay-Hooi Khoo,Kunihiko Kobayashi,Daniel Kolarich,Akihiro Kondo,Carlito B. Lebrilla,Miyako Nakano,Hisashi Narimatsu,Jan Novak,Milos V. Novotny,Erina Ohno,Nicolle H. Packer,Elizabeth Palaima,Matthew B. Renfrow,Michiko Tajiri,Kristina A. Thomsson,Hirokazu Yagi,Shin-Yi Yu,Naoyuki Taniguchi +35 more
TL;DR: An assessment of the methodologies currently used for O-glycan analysis found two general strategies were found to give the most reliable data, namely direct MS analysis of mixtures of permethylated reduced glycans in the positive ion mode and analysis of native reduced glycoproteins in the negative ion mode using LC-MS approaches.
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N-Acetylglucosaminyltransferase III Antagonizes the Effect of N-Acetylglucosaminyltransferase V on α3β1 Integrin-mediated Cell Migration
Yanyang Zhao,Takatoshi Nakagawa,Satsuki Itoh,Kei-ichiro Inamori,Tomoya Isaji,Tomoya Isaji,Yoshinobu Kariya,Akihiro Kondo,Eiji Miyoshi,Kaoru Miyazaki,Nana Kawasaki,Naoyuki Taniguchi,Jianguo Gu,Jianguo Gu +13 more
TL;DR: GnT-III and GnT-V can competitively modify the same target glycoprotein and furthermore positively or negatively regulate its biological functions for the first time.
Journal ArticleDOI
Enhanced Transglycosylation Activity of Arthrobacter protophormiae Endo-β-N-acetylglucosaminidase in Media Containing Organic Solvents (∗)
Jian-Qiang Fan,Kaoru Takegawa,Shojiro Iwahara,Akihiro Kondo,Ikunoshin Kato,Chitrananda Abeygunawardana,Yuan C. Lee +6 more
TL;DR: The transglycosylation activity of endo-β-N-acetylglucosaminidase from Arthrobacter protophormiae (endo-A) was enhanced by inclusion of organic solvents in the reaction mixture as analyzed by high performance anion exchange chromatography.