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Akio Wanaka
Researcher at Nara Medical University
Publications - 171
Citations - 7431
Akio Wanaka is an academic researcher from Nara Medical University. The author has contributed to research in topics: Gene expression & Embryonic stem cell. The author has an hindex of 47, co-authored 164 publications receiving 7024 citations. Previous affiliations of Akio Wanaka include Washington University in St. Louis & Fukushima Medical University.
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Journal ArticleDOI
Localization of FGF receptor mRNA in the adult rat central nervous system by in situ hybridization.
TL;DR: The results strongly suggest that FGF or FGF-like molecules may exert effects on specific neuronal populations in the mature CNS.
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Signalling mediated by the endoplasmic reticulum stress transducer OASIS is involved in bone formation.
Tomohiko Murakami,Atsushi Saito,Shin-ichiro Hino,Shinichi Kondo,Soshi Kanemoto,Kazuyasu Chihara,Hiroshi Sekiya,Kenji Tsumagari,Kimiko Ochiai,Kazuya Yoshinaga,Masahiro Saitoh,Riko Nishimura,Toshiyuki Yoneda,Ikuyo Kou,Tatsuya Furuichi,Shiro Ikegawa,Masahito Ikawa,Masaru Okabe,Akio Wanaka,Kazunori Imaizumi +19 more
TL;DR: The studies show that OASIS is critical for bone formation through the transcription of Col1a1 and the secretion of bone matrix proteins, and they reveal a new mechanism by which ER stress-induced signalling mediates bone formation.
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OASIS, a CREB/ATF-family member, modulates UPR signalling in astrocytes
Shinichi Kondo,Tomohiko Murakami,Tomohiko Murakami,Kouko Tatsumi,Maiko Ogata,Maiko Ogata,Soshi Kanemoto,Soshi Kanemoto,Kumi Otori,Ken Iseki,Akio Wanaka,Kazunori Imaizumi +11 more
TL;DR: P pivotal roles for OASIS in modulating the unfolded protein response in astrocytes are revealed, and the possibility that cell type-specific UPR signalling also exists in other cells is revealed.
Journal ArticleDOI
Expression of FGF receptor gene in rat development
TL;DR: In non-neuronal embryonic tissues, a wide variety of organs expressed FGF-R message, and these observations reinforce the idea that FGF exerts effects on the development of various tissues.
Journal ArticleDOI
Localization of ADAMTS13 to the stellate cells of human liver.
Masahito Uemura,Kouko Tatsumi,Masanori Matsumoto,Masao Fujimoto,Tomomi Matsuyama,Masatoshi Ishikawa,Takaaki Iwamoto,Toshio Mori,Akio Wanaka,Hiroshi Fukui,Yoshihiro Fujimura +10 more
TL;DR: Results suggest that HSCs may be major cells producing ADAMTS13 in human liver, with positive signals exclusively in perisinusoidal cells with irregularly elongated dendritic processes extending between hepatocytes.