Aleksandra Fučić

TL;DR: The best model, which included exposure to genotoxic factors, host factors, methods, and scoring criteria, explained 75% of the total variance, with the largest contribution attributable to laboratory methods.

TL;DR: In this article, an inter-laboratory slide-scoring exercise was performed among 34 laboratories from 21 countries with a total of 51 slide scorers involved, and the results of these studies indicate clearly that even after standardizing culture and scoring conditions it will be necessary to calibrate scorers and laboratories if MN, MNed cell and nucleoplasmic bridge frequencies are reliably compared among laboratories and among populations.

TL;DR: The previously reported association between level of chromosomal aberrations and cancer risk is confirmed and novel information is provided on the type of aberration more strongly predictive of cancer risk and on the types of cancer more strongly predicted by chromosome type and chromatid type.

TL;DR: Although the absolute MN frequencies obtained with automated scoring were lower as compared to those detected by visual scoring, a clear dose response for MNBN frequencies was observed with the automated scoring system, indicating that it is able to produce biologically relevant and reliable results.

TL;DR: The results of the study indicate that microwave radiation causes changes in the genome of somatic human cells and that the applied tests are equally sensitive for the detection of the genotoxicity of microwaves.