A
Alexander J. Blake
Researcher at University of Nottingham
Publications - 1136
Citations - 37892
Alexander J. Blake is an academic researcher from University of Nottingham. The author has contributed to research in topics: Crystal structure & Ligand. The author has an hindex of 89, co-authored 1133 publications receiving 35746 citations. Previous affiliations of Alexander J. Blake include University of Illinois at Chicago & University of Wisconsin-Madison.
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Journal ArticleDOI
A second generation formal synthesis of (-)-cephalotaxine.
TL;DR: A second generation formal synthesis of the alkaloid (-)-cephalotaxine has been achieved using an alkylidene carbene 1,5-CH insertion reaction to establish a key quaternary stereocenter.
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Nitrile functionalised pendant-arm derivatives of aza- and mixed donor macrocyclic ligands as new building blocks for inorganic crystal engineering
Lorenzo Tei,Lorenzo Tei,Alexander J. Blake,Paul A. Cooke,Claudia Caltagirone,Francesco Demartin,Vito Lippolis,Francesca Morale,Claire Wilson,Martin Schröder +9 more
TL;DR: A range of nitrile-functionalised pendant arm derivatives of [9]aneN3, [9]-aneN2S, [ 9]aneNS2, [12]ane NS2O and [15]aneO2N3 have been prepared as mentioned in this paper.
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Reactivity of the uranium(IV) carbene complex [U(BIPMTMS)(Cl)(μ-Cl)2Li(THF)2] (BIPMTMS = {C(PPh2NSiMe3)2}) towards carbonyl and heteroallene substrates: metallo-Wittig, adduct formation, C–F bond activation, and [2 + 2]-cycloaddition reactions
TL;DR: Complexes 2-8 have been variously characterised by single crystal X-ray diffraction, multi-nuclear NMR and FTIR spectroscopies, Evans method solution magnetic moments, variable temperature SQUID magnetometry, and elemental analyses.
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Studies towards complex bridged alkaloids: regio-and stereocontrolled enolate chemistry of 2,5-diketopiperazines
TL;DR: The substitution of symmetrical N-protected diketopiperazines (DKPs) via enolate intermediates has been studied in this article, leading to enantiopure DKP products if chiral amino acid precursors were employed, and giving racemic products, starting with centrosymmetric DKPs, even when a chiral lithium amide base was used to generate the lithium enolate.
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The structural characterisation and elucidation of the electronic structure of the mononuclear Pt(III) complex [Pt([9]aneS3)2]3+ ([9]aneS3 = 1,4,7-trithiacyclononane).
TL;DR: The mononuclear Pt(III) complex, [Pt([9]aneS(3))(2)](3+), has been isolated and characterised by X-ray crystallography; its electronic structure determined by EPR spectroscopy and DFT calculations.