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Alexander L. Gerlach
Researcher at University of Cologne
Publications - 178
Citations - 5610
Alexander L. Gerlach is an academic researcher from University of Cologne. The author has contributed to research in topics: Anxiety & Panic disorder. The author has an hindex of 38, co-authored 162 publications receiving 4748 citations. Previous affiliations of Alexander L. Gerlach include Stanford University & University of Marburg.
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Gender differences in associations of glutamate decarboxylase 1 gene (GAD1) variants with panic disorder.
Heike Weber,Claus Jürgen Scholz,Katharina Domschke,Katharina Domschke,Christian Baumann,Benedikt Klauke,Christian Jacob,Wolfgang Maier,Jürgen Fritze,Borwin Bandelow,Peter Zwanzger,Thomas Lang,Thomas Lang,Lydia Fehm,Andreas Ströhle,Alfons O. Hamm,Alexander L. Gerlach,Georg W. Alpers,Georg W. Alpers,Tilo Kircher,Hans-Ulrich Wittchen,Volker Arolt,Paul Pauli,Jürgen Deckert,Andreas Reif +24 more
TL;DR: The present study represents the first systematic evaluation of gender-specific enrichment of risk alleles of the common SNP variation in the panic disorder candidate gene GAD1 and tentative results provide a possible explanation for the higher susceptibility of females to panic disorder.
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MicroRNA hsa-miR-4717-5p regulates RGS2 and may be a risk factor for anxiety-related traits
Leif Hommers,Annette Raab,Alexandra Bohl,Heike Weber,Claus-Jürgen Scholz,Angelika Erhardt,Elisabeth B. Binder,Volker Arolt,Alexander L. Gerlach,Andrew T. Gloster,Raffael Kalisch,Tilo Kircher,Tina B. Lonsdorf,Andreas Ströhle,Peter Zwanzger,Manuel Mattheisen,Sven Cichon,Sven Cichon,Sven Cichon,Klaus-Peter Lesch,Katharina Domschke,Andreas Reif,Martin J. Lohse,Jürgen Deckert +23 more
TL;DR: Dimensional anxiety traits, as described by Anxiety Sensitivity Index and Agoraphobic Cognitions Questionnaire, were significantly higher among carriers of both major (G) alleles in a combined patient/control sample and data indicate that MIR4717 regulates human RGS2 and contributes to the genetic risk towards anxiety‐related traits.
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(Don't) panic in the scanner! How panic patients with agoraphobia experience a functional magnetic resonance imaging session.
Ulrike Lueken,Markus Muehlhan,Hans-Ulrich Wittchen,Thilo Kellermann,Isabelle Reinhardt,Carsten Konrad,Carsten Konrad,Thomas Lang,Thomas Lang,André Wittmann,Andreas Ströhle,Alexander L. Gerlach,Alexander L. Gerlach,A Ewert,Tilo Kircher +14 more
TL;DR: The feasibility of large-scale fMRI studies on PD/AG patients could be proved and future studies are needed to investigate the relationship between self-reported distress and fMRI data in patient groups that are subject to neuroimaging research.
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5HTT is associated with the phenotype psychological flexibility: results from a randomized clinical trial
Andrew T. Gloster,Andrew T. Gloster,Alexander L. Gerlach,Alfons O. Hamm,Michael Höfler,Georg W. Alpers,Tilo Kircher,Andreas Ströhle,Thomas Lang,Hans-Ulrich Wittchen,Jürgen Deckert,Andreas Reif +11 more
TL;DR: It is concluded that 5HTT polymorphism and the endophenotype psychological flexibility are important variables for the treatment of PD/AG and may help bridge genetic and psychological literatures.