A
Allan Bradley
Researcher at Wellcome Trust Sanger Institute
Publications - 385
Citations - 81969
Allan Bradley is an academic researcher from Wellcome Trust Sanger Institute. The author has contributed to research in topics: Gene & Genome. The author has an hindex of 127, co-authored 379 publications receiving 77492 citations. Previous affiliations of Allan Bradley include Howard Hughes Medical Institute & University of Texas MD Anderson Cancer Center.
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Mosaic complementation demonstrates a regulatory role for myosin VIIa in actin dynamics of stereocilia.
TL;DR: The results strongly suggest that myosin VIIa regulates the establishment of a setpoint for stereocilium heights, and this novel role may influence their normal staircase-like arrangement within a bundle.
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The piggyBac Transposon Displays Local and Distant Reintegration Preferences and Can Cause Mutations at Noncanonical Integration Sites
Meng Amy Li,Stephen J. Pettitt,Sabine E. Eckert,Zemin Ning,Stephen Rice,Juan Cadiñanos,Kosuke Yusa,Nathalie Conte,Allan Bradley +8 more
TL;DR: It is found that piggyBac preferentially integrates locally to the excision site when mobilized from a chromosomal location and identified other nonlocal regions of the genome with elevated insertion frequencies.
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Synergistic effects of inhibins and müllerian-inhibiting substance on testicular tumorigenesis.
TL;DR: It is demonstrated that inhibin and MIS synergize to influence testicular tumor development.
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Urocortin-deficient mice display normal stress-induced anxiety behavior and autonomic control but an impaired acoustic startle response.
Xiaozhong Wang,Hong Su,Leslie D. Copenhagen,Sukishi Vaishnav,Fredalina Pieri,Cynthia Shope,William E. Brownell,Mariella De Biasi,Richard Paylor,Allan Bradley +9 more
TL;DR: The results suggest that Ucn does not play an essential role in stress-induced behavioral and autonomic responses, and may modulate the acoustic startle response through the Ucn-expressing neuron projections from the region of the Edinger-Westphal nucleus.
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A powerful molecular synergy between mutant Nucleophosmin and Flt3-ITD drives acute myeloid leukemia in mice
Annalisa Mupo,Letizia Celani,Letizia Celani,Oliver M. Dovey,Jl Cooper,Carolyn Grove,Roland Rad,Paolo Sportoletti,Brunangelo Falini,Allan Bradley,Gs Vassiliou +10 more
TL;DR: It is manifest that the precise combination of driver mutations in the genome of each AML impacts on its salient features, including responsiveness to treatments and prognosis.