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Stephen J. Fowler

Researcher at University of Manchester

Publications -  234
Citations -  7806

Stephen J. Fowler is an academic researcher from University of Manchester. The author has contributed to research in topics: Asthma & Medicine. The author has an hindex of 39, co-authored 201 publications receiving 5283 citations. Previous affiliations of Stephen J. Fowler include Lancashire Teaching Hospitals NHS Foundation Trust & Manchester Academic Health Science Centre.

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Journal ArticleDOI

Genetic mechanisms of critical illness in Covid-19.

Erola Pairo-Castineira, +1449 more
- 04 Mar 2021 - 
TL;DR: The GenOMICC (Genetics Of Mortality In Critical Care) genome-wide association study in 2244 critically ill Covid-19 patients from 208 UK intensive care units is reported, finding evidence in support of a causal link from low expression of IFNAR2, and high expression of TYK2, to life-threatening disease.
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COVID-19 vaccine coverage in health-care workers in England and effectiveness of BNT162b2 mRNA vaccine against infection (SIREN): a prospective, multicentre, cohort study.

Victoria Hall, +353 more
- 08 May 2021 - 
TL;DR: The SIREN study as discussed by the authors showed that the BNT162b2 vaccine can prevent both symptomatic and asymptomatic infection in working-age adults in the UK.
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Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort

Dominick E. Shaw, +56 more
TL;DR: U-BIOPRED is characterised by poor symptom control, increased comorbidity and airway inflammation, despite high levels of treatment, and is well suited to identify asthma phenotypes using the array of "omic" datasets that are at the core of this systems medicine approach.
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A European respiratory society technical standard : exhaled biomarkers in lung disease

TL;DR: Application of breath biomarker measurement in a standardised manner will provide comparable results, thereby facilitating the potential use of these biomarkers in clinical practice, and highlighting future research priorities in the field.