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Andrea Dardis
Researcher at University of California, San Francisco
Publications - 98
Citations - 2968
Andrea Dardis is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Enzyme replacement therapy & Gene. The author has an hindex of 30, co-authored 91 publications receiving 2382 citations. Previous affiliations of Andrea Dardis include International Centre for Genetic Engineering and Biotechnology.
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Journal ArticleDOI
Cerebrospinal fluid lysosomal enzymes and alpha-synuclein in Parkinson's disease.
Lucilla Parnetti,Davide Chiasserini,Emanuele Persichetti,Paolo Eusebi,Shiji Varghese,Mohammad M. Qureshi,Andrea Dardis,Marta Deganuto,Claudia De Carlo,Anna Castrioto,Chiara Balducci,Silvia Paciotti,Nicola Tambasco,Bruno Bembi,Laura Bonanni,Marco Onofrj,Aroldo Rossi,Tommaso Beccari,Omar M. A. El-Agnaf,Paolo Calabresi +19 more
TL;DR: The results demonstrate the possibility of detecting lysosomal dysfunction in CSF and further support the need to combine different biomarkers for improving the diagnostic accuracy of PD.
Journal ArticleDOI
Consensus clinical management guidelines for Niemann-Pick disease type C.
Tarekegn Geberhiwot,Alessandro Moro,Andrea Dardis,Uma Ramaswami,Sandra Sirrs,Mercedes Pineda Marfa,Marie T. Vanier,Mark Walterfang,Shaun Bolton,Charlotte Dawson,Bénédicte Héron,Miriam Stampfer,Jackie Imrie,Christian J. Hendriksz,Paul Gissen,Ellen Crushell,Maria Josep Coll,Yann Nadjar,Hans H. Klünemann,Eugen Mengel,M. Hrebicek,Simon Jones,Daniel S. Ory,Bruno Bembi,Marc C. Patterson +24 more
TL;DR: Clinical guidelines that define standard of care for NPC patients, foster shared care arrangements between expert centres and family physicians, and empower patients are developed that can inform care providers, care funders, patients and their carers of best practice of care.
Journal ArticleDOI
Mutation profile of the GAA gene in 40 Italian patients with late onset glycogen storage disease type II.
Anna Lisa E. Montalvo,Bruno Bembi,M. Donnarumma,Mirella Filocamo,Giancarlo Parenti,Miriam Rossi,Luciano Merlini,Emanuele Buratti,P. De Filippi,Andrea Dardis,Marina Stroppiano,Giovanni Ciana,Maria Gabriela Pittis +12 more
TL;DR: The complete molecular analysis of the GAA gene performed on 40 Italian patients with late onset GSDII is reported here, with particular emphasis on the subgroup carrying the c.‐32‐13T>G/c.2237G>A genotype.
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Oxidative stress in NPC1 deficient cells: protective effect of allopregnanolone
Stefania Zampieri,Synthia H. Mellon,Terry D. Butters,Marco Nevyjel,Douglas F. Covey,Bruno Bembi,Andrea Dardis +6 more
TL;DR: It is suggested that oxidative stress might contribute to the NPC disease and allopregnanolone might be beneficial in the treatment of the disease, at least in part, due to its ability to restore the intracellular redox state.
Journal ArticleDOI
Recommendations for the detection and diagnosis of Niemann-Pick disease type C: An update
Marc C. Patterson,Peter E. Clayton,Paul Gissen,Mathieu Anheim,Peter Bauer,Olivier Bonnot,Andrea Dardis,Carlo Dionisi-Vici,Hans H. Klünemann,Philippe Latour,Charles Marques Lourenço,Daniel S. Ory,Alasdair Parker,Miguel Pocovi,Michael Strupp,Marie T. Vanier,Mark Walterfang,Thorsten Marquardt +17 more
TL;DR: This publication provides expert recommendations for clinicians who may see patients presenting with the signs and symptoms of NP-C, including general practitioners, pediatricians, neurologists, and psychiatrists, and on screening within specific at-risk patient cohorts.