L
Lucilla Parnetti
Researcher at University of Perugia
Publications - 419
Citations - 18248
Lucilla Parnetti is an academic researcher from University of Perugia. The author has contributed to research in topics: Dementia & Medicine. The author has an hindex of 63, co-authored 379 publications receiving 14294 citations. Previous affiliations of Lucilla Parnetti include university of lille.
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Journal ArticleDOI
CSF biomarkers and incipient Alzheimer disease in patients with mild cognitive impairment.
Niklas Mattsson,Henrik Zetterberg,Oskar Hansson,Niels Andreasen,Lucilla Parnetti,Michael Jonsson,Sanna-Kaisa Herukka,Wiesje M. van der Flier,Marinus A. Blankenstein,Michael Ewers,Kenneth Rich,Elmar Kaiser,Marcel M. Verbeek,Magda Tsolaki,Ezra Mulugeta,Erik Rosén,Dag Aarsland,Pieter Jelle Visser,Johannes Schröder,Jan Marcusson,Mony J. de Leon,Harald Hampel,Philip Scheltens,Tuula Pirttilä,Anders Wallin,Maria Eriksdotter Jönhagen,Lennart Minthon,Bengt Winblad,Kaj Blennow +28 more
TL;DR: This multicenter study found that CSF Abeta42, T-t Tau, and P-tau identify incipient AD with good accuracy, but less accurately than reported from single-center studies.
Journal ArticleDOI
Effect of a Novel Free Radical Scavenger, Edaravone (MCI-186), on Acute Brain Infarction
Wolfgang Müllges,Dorothea Franke,Wilko Reents,Jörg Babin-Ebell,Klaus V. Toyka,N.U. Ko,S.C. Johnston,W.L. Young,V. Singh,A.L. Klatsky,Filipa Falcão,Norbert G. Campeau,Eelco F. M. Wijdicks,John D. Atkinson,Jimmy R. Fulgham,Raymond Tak Fai Cheung,Pui W. Cheng,Wai M. Lui,Gilberto K.T. Leung,Ting-Yim Lee,Stefan T. Engelter,James M. Provenzale,Jeffrey R. Petrella,David M. DeLong,Mark J. Alberts,Stefan Evers,Darius G. Nabavi,Alexandra Rahmann,Christoph Heese,Doris Reichelt,Ingo-W. Husstedt,Antonio Arauz,Leora Velásquez,Carlos Cantú,Juan A. Nader,Mario López,Luis Murillo,Yolanda Aburto,Patrizia Nencini,Cristina Sarti,Rinaldo Innocenti,Giovanni Pracucci,Domenico Inzitari,Kyoung Heo,Sun Ah Park,Jong Yun Lee,Byung In Lee,Seung-Koo Lee,Patricia Canhão,José M. Ferro,Dénes Páll,Georgios Settakis,Éva Katona,László Csiba,György Kakuk,Martien Limburg,Dániel Bereczki,Béla Fülesdi,Maurizio Paciaroni,Valeria Caso,Gabriela Cardaioli,Francesco Corea,Paolo Milia,Michele Venti,Mohammed Hamam,Gian Piero Pelliccioli,Lucilla Parnetti,Virgilio Gallai,Thanh G. Phan,John Huston +69 more
TL;DR: Edaravone represents a neuroprotective agent which is potentially useful for treating acute ischemic stroke, since it can exert significant effects on functional outcome as compared with placebo.
Journal ArticleDOI
Neurofilament light chain as a biomarker in neurological disorders
Lorenzo Gaetani,Kaj Blennow,Paolo Calabresi,Massimiliano Di Filippo,Lucilla Parnetti,Henrik Zetterberg +5 more
TL;DR: Evidence that both CSF and blood NfL may serve as diagnostic, prognostic and monitoring biomarkers in neurological diseases is progressively increasing, and N fL is one of the most promising biomarkers to be used in clinical and research setting in the next future.
Journal ArticleDOI
New insights into the genetic etiology of Alzheimer’s disease and related dementias
Céline Bellenguez,Fahri Küçükali,Iris E. Jansen,Luca Kleineidam,Sonia Moreno-Grau,Najaf Amin,Adam C. Naj,R. Campos-Martín,Benjamin Grenier-Boley,Víctor Andrade,Peter Holmans,Anne Boland,Vincent Damotte,S. J. van der Lee,Marcos R. Costa,Teemu Kuulasmaa,Qiong Yang,Itziar de Rojas,Joshua C. Bis,Amber Yaqub,Ivana Prokic,Julien Chapuis,Shahzad Ahmad,Vilmantas Giedraitis,Dag Aarsland,Carla Abdelnour,Emilio Alarcón-Martín,Daniel Alcolea,Montserrat Alegret,Ignacio Alvarez,Victoria Alvarez,Nicola J. Armstrong,Anthoula Tsolaki,Carmen Antúnez,Ildebrando Appollonio,Marina Arcaro,Silvana Archetti,Alfonso Arias Pastor,Beatrice Arosio,Lavinia Athanasiu,Henri Bailly,Nerisa Banaj,Miquel Baquero,Sandra Barral,Alexa S. Beiser,Ana Pastor,Jennifer E. Below,Penny Benchek,Luisa Benussi,Claudine Berr,Céline Besse,Valentina Bessi,Giuliano Binetti,Alessandra Bizarro,Rafael Blesa,Mercè Boada,Eric Boerwinkle,S. Borroni,Silvia Boschi,Paola Bossù,Geir Bråthen,Jan Bressler,Catherine Bresner,Henry Brodaty,Keeley J. Brookes,Luis I. Brusco,Dolores Buiza-Rueda,Katharina Bürger,Vanessa Burholt,William S. Bush,Miguel Calero,Laura B. Cantwell,Geneviève Chêne,Jaeyoon Chung,Michael L. Cuccaro,Angel Carracedo,Roberta Cecchetti,Laura Cervera-Carles,Camille Charbonnier,Hung-Hsin Chen,Caterina Chillotti,Simona Ciccone,Jurgen A.H.R. Claassen,Christopher M. Clark,Elisa Conti,Anaïs Corma-Gómez,Emanuele Maria Costantini,Carlo Custodero,D. Daian,Maria Carolina Dalmasso,Antonio Daniele,Efthimios Dardiotis,Jean-François Dartigues,Peter Paul De Deyn,Katia de Paiva Lopes,Lot de Witte,Stéphanie Debette,Jürgen Deckert,Teodoro Del Ser,Nicola Denning,Anita L. DeStefano,Martin Dichgans,Janine Diehl-Schmid,Monica Diez-Fairen,Paolo Rosso,Srdjan Djurovic,Emmanuelle Duron,Emrah Düzel,Carole Dufouil,Gudny Eiriksdottir,Sebastiaan Engelborghs,Valentina Escott-Price,Ana Espinosa,Michael Ewers,Kelley Faber,Tagliavini Fabrizio,Sune F. Nielsen,David W. Fardo,Lucia Farotti,Chiara Fenoglio,Marta Fernández-Fuertes,Raffaele Ferrari,Catarina Beatriz Silva Ferreira,Evelyn Ferri,Bertrand Fin,Peter Fischer,Tormod Fladby,Klaus Fliessbach,Bernard Fongang,Myriam Fornage,Juan Fortea,Tatiana Foroud,Silvia Fostinelli,Nick C. Fox,Emilio Franco-Macías,María J. Bullido,Ana Frank-García,Lutz Froelich,Brian Fulton-Howard,Daniela Galimberti,José María García-Alberca,Pablo Garcia-Gonzalez,Sebastián García-Madrona,Guillermo García-Ribas,Roberta Ghidoni,Ina Giegling,Giaccone Giorgio,Alison Goate,Oliver Goldhardt,Duber Gomez-Fonseca,Antonio González-Pérez,Caroline Graff,Giulia Grande,Emma Green,Timo Grimmer,Edna Grünblatt,Michelle Grunin,Vilmundur Gudnason,Tamar Guetta-Baranes,Annakaisa Haapasalo,Georgios M. Hadjigeorgiou,Jonathan L. Haines,Kara L. Hamilton-Nelson,Harald Hampel,Olivier Hanon,John Hardy,T. Hartmann,Lucrezia Hausner,Janet C Harwood,Stefanie Heilmann-Heimbach,Seppo Helisalmi,Michael T. Heneka,Isabel Hernández,Martin J. Herrmann,Per Hoffmann,Clive Holmes,Henne Holstege,Raquel Huerto Vilas,Marc Hulsman,Jack Humphrey,Geert Jan Biessels,Xueqiu Jian,Charlotte Johansson,Gyungah Jun,Y. Kastumata,John S. K. Kauwe,Patrick G. Kehoe,Lena Kilander,Anne Kinhult Ståhlbom,Miia Kivipelto,Anne M. Koivisto,Johannes Kornhuber,Mary H. Kosmidis,Walter A. Kukull,Pavel P. Kuksa,Brian W. Kunkle,Amanda B. Kuzma,Carmen Lage,Erika J. Laukka,Lenore J. Launer,Alessandra Lauria,Chien‐Yueh Lee,Jenni Lehtisalo,Ondrej Lerch,Alberto Lleó,W. T. Longstreth,Oscar L. Lopez,Adolfo López de Munain,Seth Love,Malin Löwemark,L. Luckcuck,Kathryn L. Lunetta,Yiyi Ma,Juan Macías,Catherine A. MacLeod,Wolfgang Mader,Francesca Mangialasche,Marco Spallazzi,Marta Marquié,Rachel Marshall,Eden R. Martin,Angel Martin Montes,Carmen Martinez Rodriguez,Carlo Masullo,Richard Mayeux,Simon Head,Patrizia Mecocci,Miguel Medina,Alun Meggy,Shima Mehrabian,Silvia Mendoza,Manuel Menéndez-González,Pablo Mir,Susanne Moebus,Merel O. Mol,Laura Molina-Porcel,Laura Montrreal,Laura Morelli,Fermin Moreno,Kevin Morgan,Thomas H. Mosley,Markus M. Nöthen,Carolina Muchnik,Shubhabrata Mukherjee,Benedetta Nacmias,Tiia Ngandu,Gaël Nicolas,Børge G. Nordestgaard,Robert Olaso,Adelina Orellana,Michela Orsini,G. Ortega,Alessandro Padovani,Caffarra Paolo,Goran Papenberg,Lucilla Parnetti,Florence Pasquier,Pau Pastor,Gina M. Peloso,Alba Pérez-Cordón,Jordi Pérez-Tur,Pierre Pericard,Oliver Peters,Yolande A.L. Pijnenburg,Juan A. Pineda,Gerard Piñol-Ripoll,Claudia Pisanu,Thomas Polak,Julius Popp,Danielle Posthuma,Josef Priller,Raquel Delgado Puerta,Olivier Quenez,Inés Quintela,Jesper Qvist Thomassen,Alberto Rábano,Innocenzo Rainero,Farid Rajabli,Inez H.G.B. Ramakers,Luis Miguel Real,Marcel J. T. Reinders,Christiane Reitz,Dolly Reyes-Dumeyer,Perry G. Ridge,Steffi G. Riedel-Heller,Peter Riederer,Natalia Roberto,Eloy Rodríguez-Rodríguez,Arvid Rongve,I. Allende,Maitée Rosende-Roca,Jose Luis Royo,Elisa Rubino,Dan Rujescu,María Eugenia Sáez,Paraskevi Sakka,Ingvild Saltvedt,Angela Sanabria,M B Sánchez-Arjona,Florentino Sanchez-Garcia,Pascual Sanchez Juan,Raquel Sánchez-Valle,Sigrid Botne Sando,Chloé Sarnowski,Claudia L. Satizabal,Michela Scamosci,Nikolaos Scarmeas,Elio Scarpini,Philip Scheltens,Norbert Scherbaum,Martin Scherer,Matthias Schmid,Anja Schneider,Jonathan M. Schott,Geir Selbæk,Davide Seripa,Manuel Serrano,Jin Sha,Alexey A. Shadrin,Olivia Anna Skrobot,Susan Slifer,G. Snijders,Hilkka Soininen,Vincenzo Solfrizzi,Alina Solomon,Yeunjoo E. Song,Sandro Sorbi,Oscar Sotolongo-Grau,Gianfranco Spalletta,Annika Spottke,Alessio Squassina,Eystein Stordal,Juan Pablo Tartan,Lluís Tárraga,Niccolò Tesi,Anbupalam Thalamuthu,Tegos Thomas,Giuseppe Tosto,Latchezar Traykov,Lucio Tremolizzo,Anne Tybjærg-Hansen,André G. Uitterlinden,Abbe Ullgren,Ingun Ulstein,Sergi Valero,Otto Valladares,Christine Van Broeckhoven,Jeffery M. Vance,Badri N. Vardarajan,Aad Van Der Lugt,Jasper Van Dongen,Jeroen van Rooij,John C. van Swieten,Rik Vandenberghe,Frans R.J. Verhey,Jean-Sébastien Vidal,Jonathan Vogelgsang,Martin Vyhnalek,Michael Wagner,David Wallon,Li-San Wang,Ruiqi Wang,Leonie Weinhold,Jens Wiltfang,Gill Windle,Bob Woods,Mary Yannakoulia,Habil Zare,Yi Zhao,Xiaoling Zhang,Congcong Zhu,Miren Zulaica,Lindsay A. Farrer,Bruce M. Psaty,Mohsen Ghanbari,Towfique Raj,Perminder S. Sachdev,Karen A. Mather,Frank Jessen,M. Arfan Ikram,Alexandre de Mendonça,Jakub Hort,Magda Tsolaki,Margaret A. Pericak-Vance,Philippe Amouyel,Julie Williams,Ruth Frikke-Schmidt,Jordi Clarimón,Jean-François Deleuze,Giacomina Rossi,Sudha Seshadri,Ole A. Andreassen,Martin Ingelsson,Mikko Hiltunen,Kristel Sleegers,Gerard D. Schellenberg,Cornelia M. van Duijn,Rebecca Sims,Wiesje M. van der Flier,Agustín Ruiz,Alfredo Ramirez,Jean-Charles Lambert +401 more
TL;DR: This paper performed a two-stage genome-wide association study with 111,326 clinically diagnosed/proxy AD cases and 677,663 controls and found 75 risk loci, of which 42 were new at the time of analysis.
Journal ArticleDOI
The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers
Niklas Mattsson,Ulf Andreasson,Staffan Persson,Hiroyuki Arai,Sat Dev Batish,Sergio Bernardini,Luisella Bocchio-Chiavetto,Marinus A. Blankenstein,Maria Berrocal Carrillo,Sonia Chalbot,Els Coart,Davide Chiasserini,Neal Cutler,Gunilla Dahlfors,Stefan Duller,Anne M. Fagan,Orestes Vicente Forlenza,Giovanni B. Frisoni,Douglas Galasko,Daniela Galimberti,Harald Hampel,Aase Handberg,Michael T. Heneka,Adrianna Z. Herskovits,Sanna-Kaisa Herukka,David M. Holtzman,Christian Humpel,Bradley T. Hyman,Khalid Iqbal,Mathias Jucker,Stephan A. Kaeser,Elmar Kaiser,Elisabeth Kapaki,Daniel Kidd,Péter Klivényi,Cindy Soendersoe Knudsen,Markus P. Kummer,James Lui,Albert Lladó,Piotr Lewczuk,Qiao-Xin Li,Ralph N. Martins,Colin L. Masters,John McAuliffe,Marc Mercken,Abhay Moghekar,José Luis Molinuevo,Thomas J. Montine,William Nowatzke,Richard O'Brien,Markus Otto,George P. Paraskevas,Lucilla Parnetti,Ronald C. Petersen,David Prvulovic,Herman P M de Reus,Robert A. Rissman,Elio Scarpini,Alessandro Stefani,Hilkka Soininen,Johannes Schröder,Leslie M. Shaw,Anders Skinningsrud,Brith Skrogstad,Annette Spreer,Leda Leme Talib,Charlotte E. Teunissen,John Q. Trojanowski,Hayrettin Tumani,Robert M. Umek,Bianca Van Broeck,Hugo Vanderstichele,László Vécsei,Marcel M. Verbeek,Manfred Windisch,Jing Zhang,Henrik Zetterberg,Kaj Blennow +77 more
TL;DR: The cerebrospinal fluid biomarkers amyloid β (Aβ)‐42, total‐Tau (T‐tau), and phosphorylated‐t Tau (P‐tAU) demonstrate good diagnostic accuracy for Alzheimer's disease (AD), but there are large variations in biomarker measurements between studies, and between and within laboratories.