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Anne M. Dosey
Researcher at University of Michigan
Publications - 3
Citations - 481
Anne M. Dosey is an academic researcher from University of Michigan. The author has contributed to research in topics: DNA origami & DNA nanotechnology. The author has an hindex of 3, co-authored 3 publications receiving 418 citations. Previous affiliations of Anne M. Dosey include Life Sciences Institute.
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Journal ArticleDOI
Visualization of arrestin recruitment by a G-protein-coupled receptor
Arun K. Shukla,Gerwin Westfield,Kunhong Xiao,Rosana I. Reis,Li-Yin Huang,Prachi Tripathi-Shukla,Jiang Qian,Sheng Li,Adi Blanc,Austin N. Oleskie,Anne M. Dosey,Min Su,Cui Rong Liang,Ling Ling Gu,Jin Ming Shan,Xin Chen,Rachel Hanna,Minjung Choi,Xiao Jie Yao,Bjoern U. Klink,Alem W. Kahsai,Sachdev S. Sidhu,Shohei Koide,Pawel A. Penczek,Anthony A. Kossiakoff,Virgil L. Woods,Brian K. Kobilka,Georgios Skiniotis,Robert J. Lefkowitz +28 more
TL;DR: A strategy for forming and purifying a functional human β2AR–β-arrestin-1 complex is devised that provides a framework for better understanding the basis of GPCR regulation by arrestins.
Journal ArticleDOI
Visualization of an N-terminal fragment of von Willebrand factor in complex with factor VIII.
Andrew Yee,Austin N. Oleskie,Anne M. Dosey,Colin A. Kretz,Robert D. Gildersleeve,Somnath Dutta,Min Su,David Ginsburg,David Ginsburg,Georgios Skiniotis,Georgios Skiniotis +10 more
TL;DR: Modeling the FVIII structure into the three-dimensional EM reconstructions of [D'D3]2-FVIII ternary and quaternary complexes indicates conformational rearrangements of the F VIII C domains compared with their disposition in the unbound state.
Journal ArticleDOI
Electron Microscopic Visualization of Protein Assemblies on Flattened DNA Origami
Leena Mallik,Soma Dhakal,Joseph Nichols,Jacob P. Mahoney,Anne M. Dosey,Shuoxing Jiang,Roger K. Sunahara,Georgios Skiniotis,Nils G. Walter +8 more
TL;DR: The demonstration that protein assemblies can be constructed with high spatial precision (within ∼2 nm of their predicted position on the platforms) by using strategically flattened single-layer origami paves the way for exploiting well-defined guest molecule assemblies for biochemistry and nanotechnology applications.