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Anqi Zheng
Researcher at Chinese Academy of Sciences
Publications - 6
Citations - 281
Anqi Zheng is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Neutralization & Antibody. The author has an hindex of 3, co-authored 6 publications receiving 34 citations.
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Journal ArticleDOI
Molecular insights into receptor binding of recent emerging SARS-CoV-2 variants.
Pengcheng Han,Pengcheng Han,Pengcheng Han,Chao Su,Chao Su,Yanfang Zhang,Chongzhi Bai,Anqi Zheng,Chengpeng Qiao,Qing Wang,Sheng Niu,Sheng Niu,Qian Chen,Qian Chen,Yuqin Zhang,Weiwei Li,Hanyi Liao,Jing Li,Zengyuan Zhang,Heecheol Cho,Mengsu Yang,Xiaoyu Rong,Xiaoyu Rong,Yu Hu,Yu Hu,Niu Huang,Jinghua Yan,Qihui Wang,Xin Zhao,George F. Gao,George F. Gao,Jianxun Qi +31 more
TL;DR: In this paper, the authors examined several SARS-CoV-2 variants of concern (VOCs) including Alpha, Beta, and Gamma, and demonstrated that five variants receptor-binding domain (RBD) increased binding affinity for hACE2, and four variants pseudoviruses increased entry into susceptible cells.
Journal ArticleDOI
Binding and molecular basis of the bat coronavirus RaTG13 virus to ACE2 in humans and other species.
Kefang Liu,Xiaoqian Pan,Linjie Li,Feng Yu,Anqi Zheng,Pei Du,Pengcheng Han,Yumin Meng,Yanfang Zhang,Lili Wu,Qian Chen,Chunli Song,Yunfei Jia,Sheng Niu,Sheng Niu,Dan Lu,Chengpeng Qiao,Zhihai Chen,Dongli Ma,Xiaopeng Ma,Shuguang Tan,Xin Zhao,Jianxun Qi,George F. Gao,Qihui Wang +24 more
TL;DR: In this paper, the complex structure of the RaTG13 receptor binding domain (RBD) with human ACE2 (hACE2) was obtained and evaluated binding of RBD to 24 additional ACE2 orthologs.
Journal ArticleDOI
Neutralisation of ZF2001-elicited antisera to SARS-CoV-2 variants.
Xin Zhao,Anqi Zheng,Dedong Li,Rong Zhang,Huan Sun,Qihui Wang,George F. Gao,Pengcheng Han,Lianpan Dai +8 more
Journal ArticleDOI
The molecular basis for SARS-CoV-2 binding to dog ACE2.
Zengyuan Zhang,Yanfang Zhang,Kefang Liu,Yan Li,Qiong Lu,Qingling Wang,Yuqin Zhang,Liang Wang,Hanyi Liao,Anqi Zheng,Sufang Ma,Zheng Fan,Huifang Li,Weijin Huang,Yuhai Bi,Xin Zhao,Qihui Wang,George F. Gao,Haixia Xiao,Zhou Tong,Jianxun Qi,Yeping Sun +21 more
TL;DR: In this article, the crystal structure of RBD in complex with dACE2 and found that the total number of contact residues, contact atoms, hydrogen bonds and salt bridges at the binding interface in this complex are slightly fewer than those in the complex of the RBD and human ACE2 (hACE2).
Journal ArticleDOI
Molecular basis of cross-species ACE2 interactions with SARS-CoV-2-like viruses of pangolin origin.
Sheng Niu,Sheng Niu,Jia Wang,Bin Bai,Lili Wu,Anqi Zheng,Qian Chen,Qian Chen,Pei Du,Pengcheng Han,Yanfang Zhang,Yunfei Jia,Yunfei Jia,Chengpeng Qiao,Jianxun Qi,Wen xia Tian,Hong-Wei Wang,Qihui Wang,George F. Gao,George F. Gao +19 more
TL;DR: In this article, the spike protein receptor-binding domain (RBD) of pangolin CoVs was found to be as efficient as the SARS-CoV-2 RBD in vitro.