Azra Krek

TL;DR: PicTar, a computational method for identifying common targets of micro RNAs, is presented and widespread coordinate control executed by microRNAs is suggested, thus providing evidence for coordinate microRNA control in mammals.

TL;DR: A class of small RNAs in human cells that originate from snoRNAs and can function like miRNAs is identified, suggesting a role for ACA45-processing products in posttranscriptional gene silencing.

TL;DR: A large number of computational methods have been developed for analyzing differential gene expression in RNA-seq data as discussed by the authors, and a comprehensive evaluation of common methods using the SEQC benchmark dataset and ENCODE data.

TL;DR: The hypothesis that miRNA expression broadly contributes to tissue specificity of mRNA expression in many human tissues is supported.

TL;DR: Investigating the role of Dicer-dependent control mechanisms in B lymphocyte development found intact Ig gene rearrangements in immunoglobulin heavy (IgH) and kappa chain loci, but increased sterile transcription and usage of D(H) elements of the DSP family in IgH, and increased N sequence addition in Igkappa due to deregulated transcription of the terminal deoxynucleotidyl transferase gene.