Bálint Csoboz

TL;DR: The classic heat shock (stress) response (HSR) was originally attributed to protein denaturation, but it is observed that a deregulated HSR is found in a large number of important diseases where more detailed knowledge of the molecular mechanisms involved may offer timely opportunities for clinical interventions and new, innovative drug treatments.

TL;DR: The role of neuroinflammation in acute and chronic pathological conditions affecting the brain is summarized and the existing literature on HSP-mediated inflammatory function within the central nervous system is explored.

TL;DR: These findings lend support to both the importance of membrane remodelling and the release of lipid signals initiating stress protein response, which can operate in tandem to control the extent of the ultimate cellular thermosensitivity.

TL;DR: Evidence is provided that exploitation of ER stress can be a propitious target in defeating multidrug resistance in cancers and suggests that AgNPs are potent inhibitors of Pgp function and are promising agents for sensitizing multidrog resistant breast cancers to anticancer drugs.

TL;DR: The current review is focusing on the available data describing the presence of MCPyV in non‐MCC tumors, with an aim to provide a comprehensive overview of the corresponding literature and to discuss the potential contribution of M CPyV to non-MCC cancer in light of this.