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Bao-Xiang Zhao
Researcher at Shandong University
Publications - 272
Citations - 8357
Bao-Xiang Zhao is an academic researcher from Shandong University. The author has contributed to research in topics: Fluorescence & Pyrazole. The author has an hindex of 48, co-authored 258 publications receiving 7136 citations. Previous affiliations of Bao-Xiang Zhao include Changwon National University.
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Journal ArticleDOI
Recent progress in the development of fluorescent probes for the detection of hypochlorous acid
TL;DR: In this article, the authors summarized and highlighted the recent advances in the development and application of HOCl fluorescent probes, and divided the HOCl fluorescence probes into five parts and discussed detection mechanisms, respectively.
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Synthesis and structure-activity relationships of novel 1-arylmethyl-3-aryl-1H-pyrazole-5-carbohydrazide hydrazone derivatives as potential agents against A549 lung cancer cells.
TL;DR: A series of novel 1-arylmethyl-3-aryl-1H-pyrazole-5-carbohydrazide hydrazone derivatives were synthesized and the effects of all the compounds on A549 cell growth were investigated, showing that all compounds had almost inhibitory effects on the growth of A549 cells.
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Chloroquine inhibits cell growth and induces cell death in A549 lung cancer cells.
Chuandong Fan,Weiwei Wang,Weiwei Wang,Bao-Xiang Zhao,Shangli Zhang,Shangli Zhang,Jun-Ying Miao,Jun-Ying Miao +7 more
TL;DR: The data suggested that CQ inhibited A549 lung cancer cell growth at lower concentrations by increasing the volume of lysosomes and that PC-PLC might be involved in this process, but the data also indicated that, at higher concentrations, CQ induced apoptosis and necrosis, but at this time its ability to increase theVolume ofLysosome gradually declined, and PC- PLC might not be implicated in the process.
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A mitochondria-targeted fluorescent probe for ratiometric detection of endogenous sulfur dioxide derivatives in cancer cells
Dong-Peng Li,Zhao-Yang Wang,Xiang-Jian Cao,Jie Cui,Xin Wang,Hao-Zhong Cui,Jun-Ying Miao,Bao-Xiang Zhao +7 more
TL;DR: HCy-D showed a ratiometric, sensitive and rapid response to HSO3(-)/SO3(2-) and was successfully used for fluorescence imaging of endogenous bisulfite in HepG2 cells, which may benefit cancer diagnosis by discriminating liver cancer cells from normal liver cells.
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A new ratiometric fluorescent probe for rapid, sensitive and selective detection of endogenous hydrogen sulfide in mitochondria.
TL;DR: A new ratiometric fluorescent probe composed of a coumarin-merocyanine dyad based on the FRET mechanism showed clear dual-emission signal changes in blue and red spectral windows upon addition of H2S in a dose dependent manner under a single wavelength excitation.