Jun-Ying Miao

TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.

TL;DR: A series of novel 1-arylmethyl-3-aryl-1H-pyrazole-5-carbohydrazide hydrazone derivatives were synthesized and the effects of all the compounds on A549 cell growth were investigated, showing that all compounds had almost inhibitory effects on the growth of A549 cells.

TL;DR: The data suggested that CQ inhibited A549 lung cancer cell growth at lower concentrations by increasing the volume of lysosomes and that PC-PLC might be involved in this process, but the data also indicated that, at higher concentrations, CQ induced apoptosis and necrosis, but at this time its ability to increase theVolume ofLysosome gradually declined, and PC- PLC might not be implicated in the process.

TL;DR: HCy-D showed a ratiometric, sensitive and rapid response to HSO3(-)/SO3(2-) and was successfully used for fluorescence imaging of endogenous bisulfite in HepG2 cells, which may benefit cancer diagnosis by discriminating liver cancer cells from normal liver cells.