Bao-Xiang Zhao

TL;DR: In this article, the authors summarized and highlighted the recent advances in the development and application of HOCl fluorescent probes, and divided the HOCl fluorescence probes into five parts and discussed detection mechanisms, respectively.

TL;DR: A series of novel 1-arylmethyl-3-aryl-1H-pyrazole-5-carbohydrazide hydrazone derivatives were synthesized and the effects of all the compounds on A549 cell growth were investigated, showing that all compounds had almost inhibitory effects on the growth of A549 cells.

TL;DR: The data suggested that CQ inhibited A549 lung cancer cell growth at lower concentrations by increasing the volume of lysosomes and that PC-PLC might be involved in this process, but the data also indicated that, at higher concentrations, CQ induced apoptosis and necrosis, but at this time its ability to increase theVolume ofLysosome gradually declined, and PC- PLC might not be implicated in the process.

TL;DR: HCy-D showed a ratiometric, sensitive and rapid response to HSO3(-)/SO3(2-) and was successfully used for fluorescence imaging of endogenous bisulfite in HepG2 cells, which may benefit cancer diagnosis by discriminating liver cancer cells from normal liver cells.

TL;DR: A new ratiometric fluorescent probe composed of a coumarin-merocyanine dyad based on the FRET mechanism showed clear dual-emission signal changes in blue and red spectral windows upon addition of H2S in a dose dependent manner under a single wavelength excitation.