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Brett D. Arnoldo
Researcher at University of Texas Southwestern Medical Center
Publications - 84
Citations - 3834
Brett D. Arnoldo is an academic researcher from University of Texas Southwestern Medical Center. The author has contributed to research in topics: Poison control & Total body surface area. The author has an hindex of 30, co-authored 81 publications receiving 3338 citations. Previous affiliations of Brett D. Arnoldo include University of Wisconsin-Madison & Parkland Memorial Hospital.
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Journal ArticleDOI
A genomic storm in critically injured humans
Wenzhong Xiao,Wenzhong Xiao,Michael N. Mindrinos,Junhee Seok,Joseph Cuschieri,Alex G. Cuenca,Hong Gao,Douglas L. Hayden,Laura Hennessy,Ernest E. Moore,Joseph P. Minei,Paul E. Bankey,Jeffrey L. Johnson,Jason L. Sperry,Avery B. Nathens,Timothy R. Billiar,Michael West,Bernard H. Brownstein,Philip H. Mason,Henry V. Baker,Celeste C. Finnerty,Marc G. Jeschke,M. Cecilia Lopez,Matthew B. Klein,Richard L. Gamelli,Nicole S. Gibran,Brett D. Arnoldo,Weihong Xu,Yuping Zhang,Steven E. Calvano,Grace P. McDonald-Smith,David A. Schoenfeld,John D. Storey,J. Perren Cobb,H. Shaw Warren,Lyle L. Moldawer,David N. Herndon,Stephen F. Lowry,Ronald V. Maier,Ronald W. Davis,Ronald G. Tompkins,W. Xiao,M. Mindrinos,J. Seok,J. Cuschieri,R. Tompkins,Roger J. Davis,R. Maier,L. Moldawer,L. Hennessy,E. Moore,J. Minei,P. Bankey,J. Johnson,J. Sperry,A. Nathens,T. Billiar,M. West,B. Brownstein,D. Herndon,H. Baker,C. Finnerty,M. Jeschke,M. Lopez,M. Klein,R. Gamelli,N. Gibran,B. Arnoldo,G. McDonald-Smith,D. Schoenfeld,J. P. Cobb,Shaw Warren,A. Cuenca,S. Lowry,S. Calvano,Doug Hayden,P. Mason,H. Gao,J. Storey,Lily L. Altstein,Ulysses J. Balis,David G. Camp,K. De Asit,Brian G. Harbrecht,Shari Honari,Bruce A. McKinley,Carol L. Miller-Graziano,Frederick A. Moore,Grant E. O'Keefe,Laurence G. Rahme,Daniel G. Remick,Michael B. Shapiro,Richard D. Smith,Robert Tibshirani,Mehmet Toner,Bram Wispelwey,Wing Hung Wong +96 more
TL;DR: It is shown that critical injury in humans induces a genomic storm with simultaneous changes in expression of innate and adaptive immunity genes that alter the status of these genes in the immune system.
Journal ArticleDOI
The Association Between Fluid Administration and Outcome Following Major Burn: A Multicenter Study
Matthew B. Klein,Douglas Hayden,Constance Elson,Avery B. Nathens,Richard L. Gamelli,Nicole S. Gibran,David N. Herndon,Brett D. Arnoldo,Geoff Silver,David A. Schoenfeld,Ronald G. Tompkins +10 more
TL;DR: Patients who received larger volumes of resuscitation fluid were at higher risk for injury complications and death, and TBSA, age, weight, and intubation status on admission were significant predictors of fluid received.
Journal ArticleDOI
Electrical injuries: A 20-year review
TL;DR: High-voltage injuries in particular have far reaching social and economic impact largely because of the patient population at greatest risk, that is, younger men at the height of their earning potential, and injury prevention remains difficult in this group because of occupation-related risk.
Journal ArticleDOI
Temporal Cytokine Profiles in Severely Burned Patients: A Comparison of Adults and Children
Celeste C. Finnerty,Marc G. Jeschke,David N. Herndon,Richard L. Gamelli,Nicole S. Gibran,Matthew B. Klein,Geoff Silver,Brett D. Arnoldo,Daniel G. Remick,Ronald G. Tompkins +9 more
TL;DR: The dramatic discrepancies observed in plasma cytokine detection between children and adults suggest that these two patient populations may benefit from different therapeutic interventions to achieve attenuation of the post-burn inflammatory response.
Journal ArticleDOI
Morbidity and survival probability in burn patients in modern burn care.
Marc G. Jeschke,Ruxandra Pinto,Robert Kraft,Robert Kraft,Avery B. Nathens,Celeste C. Finnerty,Celeste C. Finnerty,Richard L. Gamelli,Nicole S. Gibran,Matthew B. Klein,Brett D. Arnoldo,Ronald G. Tompkins,David N. Herndon,David N. Herndon +13 more
TL;DR: In the modern burn care setting, adults with over 40% total body surface area burned and children with over 60% total Body Surface Area burned are at high risk for morbidity and mortality, even in highly specialized centers.