Wenzhong Xiao

TL;DR: This study shows that, although acute inflammatory stresses from different etiologies result in highly similar genomic responses in humans, the responses in corresponding mouse models correlate poorly with the human conditions and also, one another.

TL;DR: This work explores the known genome-wide interaction network to identify significant functional modules perturbed in response to an inflammatory stimulus and reveals that the human blood leukocyte response to acute systemic inflammation includes the transient dysregulation of leukocytes bioenergetics and modulation of translational machinery.

TL;DR: The very accurate data show that the positron fraction is steadily increasing from 10 to ∼ 250 GeV, but, from 20 to 250 GeV, the slope decreases by an order of magnitude, showing the existence of new physical phenomena.

TL;DR: It is shown that critical injury in humans induces a genomic storm with simultaneous changes in expression of innate and adaptive immunity genes that alter the status of these genes in the immune system.

TL;DR: The complete SEQC data sets, comprising >100 billion reads, provide unique resources for evaluating RNA-seq analyses for clinical and regulatory settings, and measurement performance depends on the platform and data analysis pipeline, and variation is large for transcript-level profiling.