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Brianne O. Petritis
Researcher at Arizona State University
Publications - 25
Citations - 1451
Brianne O. Petritis is an academic researcher from Arizona State University. The author has contributed to research in topics: Proteomics & Proteome. The author has an hindex of 17, co-authored 25 publications receiving 1352 citations. Previous affiliations of Brianne O. Petritis include University of California, San Francisco & Environmental Molecular Sciences Laboratory.
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Journal ArticleDOI
A systems approach to prion disease
Daehee Hwang,Daehee Hwang,Inyoul Lee,Hyuntae Yoo,Nils Gehlenborg,Nils Gehlenborg,Ji-Hoon Cho,Brianne O. Petritis,David Baxter,Rose Pitstick,Rebecca L. Young,Doug Spicer,Nathan D. Price,John G. Hohmann,Stephen J. DeArmond,George A. Carlson,Leroy Hood +16 more
TL;DR: This work tracked global gene expression in the brains of eight distinct mouse strain–prion strain combinations throughout the progression of the disease to capture the effects of prion strain, host genetics, and PrP concentration on disease incubation time and suggests some possible therapeutic approaches.
Journal ArticleDOI
Enhanced Detection of Low Abundance Human Plasma Proteins Using a Tandem IgY12-SuperMix Immunoaffinity Separation Strategy
Wei-Jun Qian,David T. Kaleta,Brianne O. Petritis,Hongliang Jiang,Tao Liu,Xu Zhang,Heather M. Mottaz,Susan M. Varnum,David G. Camp,Lei Huang,Xiangming Fang,Wei-Wei Zhang,Richard D. Smith +12 more
TL;DR: The proposed tandem IgY12-SuperMix immunoaffinity separation system separates ∼60 abundant proteins from the low abundance proteins in plasma, allowing for significant enrichment of low abundance plasma proteins in the SuperMix flow-through fraction.
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Clinical Microfluidics for Neutrophil Genomics and Proteomics
Kenneth T. Kotz,Wenzong Xiao,Wenzong Xiao,Carol L. Miller-Graziano,Wei-Jun Qian,Aman Russom,Elizabeth A. Warner,Lyle L. Moldawer,Asit De,Paul E. Bankey,Brianne O. Petritis,David G. Camp,Alan E. Rosenbach,Jeremy Goverman,Shawn P. Fagan,Bernard H. Brownstein,Daniel Irimia,Weihong Xu,Julie Wilhelmy,Michael N. Mindrinos,Richard D. Smith,Ronald W. Davis,Ronald G. Tompkins,Mehmet Toner +23 more
TL;DR: The preliminary results from a small cohort of subjects in this study and healthy controls show a unique time-dependent gene expression pattern clearly demonstrating the ability of this tool to discriminate temporal transcriptional events of neutrophils within a clinical setting.
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Quantitative proteomics analysis of adsorbed plasma proteins classifies nanoparticles with different surface properties and size
Haizhen Zhang,Kristin E. Burnum,Maria L. Luna,Brianne O. Petritis,Jong-Seo Kim,Wei-Jun Qian,Ronald J. Moore,Alejandro Heredia-Langner,Bobbie-Jo M. Webb-Robertson,Brian D. Thrall,David G. Camp,Richard D. Smith,Joel G. Pounds,Tao Liu +13 more
TL;DR: The comprehensive quantitative proteomics results obtained in this study provide rich data for computational modeling and have potential implications towards predicting nanoparticle biocompatibility.
Journal ArticleDOI
Global systems-level analysis of Hfq and SmpB deletion mutants in Salmonella: implications for virulence and global protein translation.
Charles Ansong,Hyunjin Yoon,Steffen Porwollik,Heather M. Mottaz-Brewer,Brianne O. Petritis,Navdeep Jaitly,Joshua N. Adkins,Michael McClelland,Fred Heffron,Richard D. Smith +9 more
TL;DR: It is shown that mutants of hfq and smpB directly or indirectly modulate at least 20% and 4% of all possible Salmonella proteins, respectively, with limited correlation between transcription and protein expression.