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Carl W. Schmid
Researcher at University of California, Davis
Publications - 102
Citations - 8705
Carl W. Schmid is an academic researcher from University of California, Davis. The author has contributed to research in topics: Alu element & Gene. The author has an hindex of 48, co-authored 102 publications receiving 8524 citations. Previous affiliations of Carl W. Schmid include University of California, Berkeley.
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Base sequence studies of 300 nucleotide renatured repeated human DNA clones
TL;DR: The nucleotide sequences of 15 clones constructed from these 300 nucleotide S 1 -resistant repeats are determined and ten of these cloned sequences are members of the Alu family of interspersed repeats, a dimeric structure that was evidently formed from a head to tail duplication of an ancestral monomeric sequence.
Journal ArticleDOI
The Alu family of dispersed repetitive sequences
Carl W. Schmid,Warren R. Jelinek +1 more
TL;DR: Property of this repeat sequence, its flanking sequences in chromosomal DNA, and RNA's transcribed from it suggest that it may be a mobile DNA element inserted at hundreds of thousands of different chromosomal locations.
Journal ArticleDOI
Ubiquitous, interspersed repeated sequences in mammalian genomes
Warren Jelinek,Thomas P. Toomey,Leslie A. Leinwand,Craig H. Duncan,P. A. Biro,Prabhakara V. Choudary,Sherman M. Weissman,Carol M. Rubin,Catherine M. Houck,Prescott L. Deininger,Carl W. Schmid +10 more
TL;DR: It is demonstrated that a portion of this highly conserved segment of repetitive mamalian DNA sequence is similar to a sequence found within a low molecular weight RNA that hydrogen-bonds to poly(A)-terminated RNA molecules of Chinese hamsters and a sequence that forms half of a perfect inverted repeat near the origin of DNA replication in papovaviruses.
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Sequence-specific packaging of DNA in human sperm chromatin
TL;DR: The existence of sequence-specific nucleohistone and nucleoprotamine components within the human spermatozoon was demonstrated by cloning size-selected single-copy sequences and by using the derived clones as probes of nucleohistsone DNA and nucleobrotamine DNA.
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A ubiquitous family of repeated DNA sequences in the human genome.
TL;DR: It is found that at least half of the 300-nucleotide duplex regions in inverted repeated sequences also have a cleavage site for the restriction enzyme Alu I, implying that the interspersion pattern of repeated and single copy sequences in human DNA is largely dominated by one family of repeated sequences.