Carlos Fernandes

TL;DR: The origin and epidemic history of ZIKV in Brazil and the Americas remain poorly understood, despite the value of this information for interpreting observed trends in reported microcephaly and other birth defects as mentioned in this paper.

TL;DR: In this article, superparamagnetic ferrite nanoparticles (MFe2O4, where M = Fe, Co, Mn) were synthesized through a novel one-step aqueous coprecipitation method based on the use of a new type of alkaline agent: the alkanolamines isopropanolamine and diisopropanoamine.

TL;DR: Analyses of viral genomes with ecological and epidemiological data yield an estimate that ZikV was present in northeast Brazil by February 2014 and is likely to have disseminated from there, nationally and internationally, before the first detection of ZIKV in the Americas.

TL;DR: HBV-specific T cells with different target specificities are characterised by distinct phenotypical and functional profiles, which have direct implications for the design of immunological studies in HBV infection, and are potentially relevant for informing immunotherapeutic approaches to induce functional cure.

TL;DR: Computational docking studies provided insights into enzyme-inhibitor interactions and a rationale for the observed selectivity and potency, and compound 27 stands out due to its favorable toxicological profile and physicochemical properties, which pointed toward blood-brain barrier permeability, thus being a valid candidate for subsequent animal studies.