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Carlos Ortiz de Solórzano

Researcher at University of Navarra

Publications -  6
Citations -  915

Carlos Ortiz de Solórzano is an academic researcher from University of Navarra. The author has contributed to research in topics: Chemistry & Luciferase. The author has an hindex of 4, co-authored 5 publications receiving 762 citations.

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Journal ArticleDOI

Evaluation of bioluminescent imaging for noninvasive monitoring of colorectal cancer progression in the liver and its response to immunogene therapy.

TL;DR: Individualized quantification of light emission was able to determine the extent and duration of antitumor responses and to predict long-term disease-free survival, showing that BLI is a rapid, convenient and safe technique for the individual monitorization of tumor progression in the liver.
Journal ArticleDOI

Phenotypic and metabolic features of mouse diaphragm and gastrocnemius muscles in chronic lung carcinogenesis: influence of underlying emphysema

TL;DR: In this model of lung carcinogenesis with and without emphysema, reduced body weight gain and muscle atrophy were observed in respiratory and limb muscles of mice after 20- and 35-week exposure times most likely through increased nuclear apoptosis and autophagy.
Posted ContentDOI

Targeting aberrant DNA methylation in mesenchymal stromal cells as a treatment for myeloma bone disease

TL;DR: It is demonstrated that not only was aberrant DNA methylation a main contributor to bone formation impairment found in MM patients, but also its targeting by CM-272 was able to reverse MM-associated bone loss and prevent myeloma- associated bone loss in a mouse model of bone marrow-disseminated MM.
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Brainstem neuromelanin and iron MRI reveals a precise signature for idiopathic and LRRK2 Parkinson’s disease

TL;DR: In this paper , a 3D automated MRI atlas-based segmentation pipeline (3D-ABSP) for NM/iron-sensitive MRI images topographically characterized the substantia nigra pars compacta (SNc) and locus coeruleus (LC) neuronal loss and calculated NM/IR contrast ratio (CR) and normalized volume (nVol).