S
Spencer L. Shorte
Researcher at Pasteur Institute
Publications - 103
Citations - 8024
Spencer L. Shorte is an academic researcher from Pasteur Institute. The author has contributed to research in topics: Gene expression & Immune system. The author has an hindex of 33, co-authored 99 publications receiving 6491 citations. Previous affiliations of Spencer L. Shorte include Centre national de la recherche scientifique & Medical University of South Carolina.
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Journal ArticleDOI
TrackMate: An open and extensible platform for single-particle tracking.
Jean-Yves Tinevez,Nick Perry,Johannes Schindelin,Genevieve M. Hoopes,Gregory D. Reynolds,Emmanuel Laplantine,Sebastian Y. Bednarek,Spencer L. Shorte,Kevin W. Eliceiri +8 more
TL;DR: TrackMate is an extensible platform where developers can easily write their own detection, particle linking, visualization or analysis algorithms within the TrackMate environment and is validated for quantitative lifetime analysis of clathrin-mediated endocytosis in plant cells.
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Objective comparison of particle tracking methods
Nicolas Chenouard,Ihor Smal,Fabrice de Chaumont,Martin Maška,Martin Maška,Ivo F. Sbalzarini,Yuanhao Gong,Janick Cardinale,Craig Carthel,Stefano Coraluppi,Mark R. Winter,Andrew R. Cohen,William J. Godinez,Karl Rohr,Yannis Kalaidzidis,Liang Liang,James S. Duncan,Hongying Shen,Yingke Xu,Klas E. G. Magnusson,Joakim Jalden,Helen M. Blau,Perrine Paul-Gilloteaux,Philippe Roudot,Charles Kervrann,François Waharte,Jean-Yves Tinevez,Spencer L. Shorte,Joost Willemse,Katherine Celler,Gilles P. van Wezel,Han-Wei Dan,Yuh-Show Tsai,Carlos Ortiz de Solórzano,Jean-Christophe Olivo-Marin,Erik Meijering +35 more
TL;DR: Although no single method performed best across all scenarios, the results revealed clear differences between the various approaches, leading to notable practical conclusions for users and developers.
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Quantitative imaging of Plasmodium transmission from mosquito to mammal
Rogerio Amino,Rogerio Amino,Sabine Thiberge,Béatrice Martin,Susanna Celli,Spencer L. Shorte,Friedrich Frischknecht,Friedrich Frischknecht,Robert Ménard +8 more
TL;DR: It is shown that only a proportion of the parasites enter blood capillaries, whereas others are drained by lymphatics, andymph sporozoites stop at the proximal lymph node, where most are degraded inside dendritic leucocytes, but some can partially differentiate into exoerythrocytic stages.
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Telomeric Heterochromatin Propagation and Histone Acetylation Control Mutually Exclusive Expression of Antigenic Variation Genes in Malaria Parasites
Lucio H. Freitas-Junior,Rosaura Hernández-Rivas,Stuart A. Ralph,Dvorak Montiel-Condado,Omar K. Ruvalcaba-Salazar,Ana Paola Rojas-Meza,Liliana Mâncio-Silva,Ricardo J. Leal-Silvestre,Alisson M. Gontijo,Spencer L. Shorte,Artur Scherf +10 more
TL;DR: The data demonstrate that mutually exclusive transcription of var genes is linked to the dynamic remodeling of chromatin, and this work identifies chromatin modifications at telomeres that spread far into telomere-proximal regions, including var gene loci (>50 kb).
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Myosin VIIa, harmonin and cadherin 23, three Usher I gene products that cooperate to shape the sensory hair cell bundle
Batiste Boëda,Aziz El-Amraoui,Amel Bahloul,Richard J. Goodyear,Laurent Daviet,Stéphane Blanchard,Isabelle Perfettini,Karl R. Fath,Karl R. Fath,Spencer L. Shorte,Jan Reiners,Anne Houdusse,Pierre Legrain,Uwe Wolfrum,Guy P. Richardson,Christine Petit +15 more
TL;DR: It is proposed that the shaping of the hair bundle relies on a functional unit composed of myosin VIIa, harmonin b and cadherin 23 that is essential to ensure the cohesion of the stereocilia.