C
Caroline Dean
Researcher at John Innes Centre
Publications - 239
Citations - 34351
Caroline Dean is an academic researcher from John Innes Centre. The author has contributed to research in topics: Arabidopsis & Flowering Locus C. The author has an hindex of 90, co-authored 223 publications receiving 31556 citations. Previous affiliations of Caroline Dean include University of California, San Diego & DuPont Pioneer.
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Journal ArticleDOI
Genome-wide association study of 107 phenotypes in Arabidopsis thaliana inbred lines
Susanna Atwell,Yu S. Huang,Bjarni J. Vilhjálmsson,Glenda Willems,Matthew W. Horton,Yan Li,Dazhe Meng,Alexander Platt,Aaron M. Tarone,Tina T. Hu,Rong Jiang,N. Wayan Muliyati,Xu Zhang,Muhammad Ali Amer,Ivan Baxter,Benjamin Brachi,Joanne Chory,Joanne Chory,Caroline Dean,Marilyne Debieu,Juliette de Meaux,Joseph R. Ecker,Nathalie Faure,Joel M. Kniskern,Jonathan D. G. Jones,Todd P. Michael,Adnane Nemri,Fabrice Roux,Fabrice Roux,David E. Salt,Chunlao Tang,Marco Todesco,M. Brian Traw,Detlef Weigel,Paul Marjoram,Justin O. Borevitz,Joy Bergelson,Magnus Nordborg +37 more
TL;DR: This study demonstrates the feasibility of GWA studies in A. thaliana and suggests that the approach will be appropriate for many other organisms, particularly when inbred lines are available.
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Transgenic plants protected from insect attack
Mark Vaeck,Arlette Reynaerts,Herman Höfte,Stefan Jansens,Marc De Beuckeleer,Caroline Dean,Caroline Dean,Marc Zabeau,Marc Van Montagu,Jan Leemans +9 more
TL;DR: The Gram-positive bacterium Bacillus thuringiensis produces proteins which are specifically toxic to a variety of insect species, and modified genes have been derived from bt2, a toxin gene cloned from one Bacillus strain.
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Arabidopsis, the Rosetta stone of flowering time?
Gordon G. Simpson,Caroline Dean +1 more
TL;DR: An integrated network of pathways that quantitatively control the timing of this developmental switch in Arabidopsis are identified and this framework provides the basis to understand the evolution of different reproductive strategies and how floral pathways interact through seasonal progression.
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Molecular Analysis of FRIGIDA, a Major Determinant of Natural Variation in Arabidopsis Flowering Time
TL;DR: This work cloned FRI and analyzed the molecular basis of the allelic variation at the FRIGIDA locus, finding that loss-of-function mutations at FRI have provided the basis for the evolution of many early-flowering ecotypes.
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Vernalization requires epigenetic silencing of FLC by histone methylation
Ruth Bastow,Joshua S. Mylne,Clare Lister,Zachary B. Lippman,Robert A. Martienssen,Caroline Dean +5 more
TL;DR: It is shown that vernalization causes changes in histone methylation in discrete domains within the FLC locus, increasing dimethylation of lysines 9 and 27 on histone H3, which identify silenced chromatin states in Drosophila and human cells.