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Charles M. Perou
Researcher at University of North Carolina at Chapel Hill
Publications - 645
Citations - 235604
Charles M. Perou is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 156, co-authored 573 publications receiving 202951 citations. Previous affiliations of Charles M. Perou include North Carolina Central University & University of Chicago.
Papers
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Journal ArticleDOI
TU-AB-BRA-08: Radiomics in the Analysis of Breast Cancer Heterogeneity On DCE-MRI
Hui Li,Hui Li,Li Lan,Li Lan,Karen Drukker,Karen Drukker,Charles M. Perou,Charles M. Perou,Maryellen L. Giger,Maryellen L. Giger +9 more
TL;DR: Computer-extracted image-based phenotypes show promise as a means for high-throughput discrimination of breast cancer molecular subtypes and there is a positive trend for enhancement texture for the various molecular sub types.
Book ChapterDOI
Chédiak–Higashi Syndrome
Charles M. Perou,Jerry Kaplan +1 more
TL;DR: The Chediak-Higashi syndrome (CHS) as discussed by the authors is a rare autosomal recessive disorder that causes hypopigmentation, recurrent infections, mild coagulation defects and varying neurologic problems.
Journal ArticleDOI
Prognostic and Predictive Value of Immune-Related Gene Expression Signatures vs Tumor-Infiltrating Lymphocytes in Early-Stage ERBB2/HER2-Positive Breast Cancer
Aranzazu Fernandez-Martinez,Tomás Pascual,Baljit Singh,Paolo Nuciforo,Naim U. Rashid,Karla V. Ballman,J. Campbell,Katherine A. Hoadley,Patricia A. Spears,Laia Paré,Fara Brasó-Maristany,Nuria Chic,Ian E. Krop,Ann H. Partridge,Javier Cortes,Antonio Llombart-Cussac,Aleix Prat,Charles M. Perou,Lisa A. Carey +18 more
TL;DR: In this paper , a combined correlative analysis of the CALGB 40601 and PAMELA trials was conducted, 305 patients with early-stage ERBB2/HER2-positive breast cancer, 6 B-cell-related signatures were more strongly associated with pathologic complete response than were tumor-infiltrating lymphocytes.
Journal ArticleDOI
12omolecular subtype of breast cancer metastases significantly influences patient post-relapse survival
Nicholas P. Tobin,J. C. Harrell,S. Egyhazi Brage,M. Frostvik Stolt,Charles M. Perou,Jonas Bergh,Thomas Hatschek,Linda S. Lindström +7 more
Patent
Methods and Kits for Predicting Outcome and Methods and Kits for Treating Breast Cancer with Radiation Therapy
TL;DR: In this article, the authors describe methods and kits for screening subjects with breast cancer to determine if the breast cancer will be responsive to a post-mastectomy breast cancer therapy including radiation.