Charles M. Perou

TL;DR: Improved metastasis-free/progression-free survival was correlated with B-cell gene expression signatures, which were restricted mainly to the basal-like and HER2-enriched breast cancer subtypes and the immunoreactive ovarian cancer subtype, suggesting the presence of a productive and potentially restricted antitumor B- cell response in basal- like breast and immunore active ovarian cancers.

TL;DR: It is reported that transformation of EpCAM+ epithelial cells results in the formation of common forms of human breast cancer, including estrogen receptor-positive and estrogen receptors-negative tumors with luminal and basal-like characteristics, respectively, whereas transformation of CD10+ cells results

TL;DR: The proposed normalization method is applied to three existing breast cancer datasets, and is compared to several competing normalization methods using the proposed validation measures.

TL;DR: It is demonstrated that microRNA-30c is transcriptionally regulated by GATA3 in breast tumours and inversely correlates with interleukin-11 expression in primary breast tumour patients, and low interleuko-11 correlates with relapse-free survival in breast cancer patients.

TL;DR: A molecular link between thymoma and the autoimmune disease myasthenia gravis is identified, characterized by tumoral overexpression of muscle autoantigens, and increased aneuploidy.