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Charlie Jennison
Researcher at Walter and Eliza Hall Institute of Medical Research
Publications - 16
Citations - 704
Charlie Jennison is an academic researcher from Walter and Eliza Hall Institute of Medical Research. The author has contributed to research in topics: Plasmodium falciparum & Plasmodium vivax. The author has an hindex of 8, co-authored 14 publications receiving 578 citations. Previous affiliations of Charlie Jennison include University of Melbourne & University of London.
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Journal ArticleDOI
Two Nonrecombining Sympatric Forms of the Human Malaria Parasite Plasmodium ovale Occur Globally
Colin J. Sutherland,Naowarat Tanomsing,Debbie Nolder,Mary C. Oguike,Charlie Jennison,Sasithon Pukrittayakamee,Christiane Dolecek,Tran Tinh Hien,Virgílio E. do Rosário,Ana Paula Arez,João Pinto,Pascal Michon,Ananias A. Escalante,François Nosten,François Nosten,Martina Burke,Rogan Lee,Marie Blaze,Thomas D. Otto,John W. Barnwell,Arnab Pain,John D. Williams,Nicholas J. White,Nicholas J. White,Nicholas P. J. Day,Nicholas P. J. Day,Georges Snounou,Georges Snounou,Peter J. Lockhart,Peter L. Chiodini,Mallika Imwong,Spencer D. Polley +31 more
TL;DR: It is proposed that P. ovale comprises 2 nonrecombining species that are sympatric in Africa and Asia and speculate on possible scenarios that could have led to this speciation.
Journal ArticleDOI
Cell Traversal Activity Is Important for Plasmodium falciparum Liver Infection in Humanized Mice
Annie S. P. Yang,Annie S. P. Yang,Matthew T. O'Neill,Charlie Jennison,Charlie Jennison,Sash Lopaticki,Cody C. Allison,Cody C. Allison,Jennifer S. Armistead,Jennifer S. Armistead,Sara M. Erickson,Sara M. Erickson,Kelly L. Rogers,Kelly L. Rogers,Andrew M. Ellisdon,Andrew M. Ellisdon,James C. Whisstock,James C. Whisstock,Rebecca E. Tweedell,Rhoel R. Dinglasan,Donna N. Douglas,Norman M. Kneteman,Justin A Boddey,Justin A Boddey +23 more
TL;DR: It is demonstrated that SPECT and perforin-like protein 1 (PLP1) are critical for transcellular migration by P. falciparum sporozoites and demonstrates the importance of cell traversal for liver infection by this human pathogen.
Journal ArticleDOI
Plasmodium vivax Populations Are More Genetically Diverse and Less Structured than Sympatric Plasmodium falciparum Populations
Charlie Jennison,Alicia Arnott,Natacha Tessier,Livingstone Tavul,Cristian Koepfli,Ingrid Felger,Peter Siba,John C. Reeder,Melanie Bahlo,Ivo Mueller,Alyssa E. Barry +10 more
TL;DR: This research clearly demonstrates how population genetic analyses can reveal deeper insight into transmission patterns than traditional surveillance methods and underlines suggestions that more intensive and sustained interventions will be needed to control and eventually eliminate P. vivax.
Journal ArticleDOI
Increasingly inbred and fragmented populations of Plasmodium vivax associated with the eastward decline in malaria transmission across the Southwest Pacific.
Andreea Waltmann,Andreea Waltmann,Cristian Koepfli,Cristian Koepfli,Natacha Tessier,Natacha Tessier,Stephan Karl,Stephan Karl,Abebe A. Fola,Abebe A. Fola,Andrew Waleluma Darcy,Lyndes Wini,G. L. Abby Harrison,G. L. Abby Harrison,Céline Barnadas,Céline Barnadas,Charlie Jennison,Charlie Jennison,Harin Karunajeewa,Harin Karunajeewa,Sarah Boyd,Maxine Whittaker,James W. Kazura,Melanie Bahlo,Melanie Bahlo,Ivo Mueller,Ivo Mueller,Ivo Mueller,Alyssa E. Barry,Alyssa E. Barry +29 more
TL;DR: It is concluded that control efforts will eventually impact P. vivax population structure and with sustained pressure, populations may eventually fragment into a limited number of clustered foci that could be targeted for elimination.
Journal ArticleDOI
Protein O-fucosylation in Plasmodium falciparum ensures efficient infection of mosquito and vertebrate hosts
Sash Lopaticki,Annie S. P. Yang,Annie S. P. Yang,Annie S. P. Yang,Alan John,Alan John,Nichollas E. Scott,James P. Lingford,Matthew T. O'Neill,Sara M. Erickson,Sara M. Erickson,Nicole C. McKenzie,Nicole C. McKenzie,Charlie Jennison,Charlie Jennison,Lachlan Whitehead,Lachlan Whitehead,Donna N. Douglas,Norman M. Kneteman,Ethan D. Goddard-Borger,Ethan D. Goddard-Borger,Justin A Boddey,Justin A Boddey +22 more
TL;DR: POFUT2 plays a similar role in malaria parasites to that in metazoans: it ensures the trafficking of Plasmodium TSR proteins as part of a non-canonical glycosylation-dependent endoplasmic reticulum protein quality control mechanism.