C
Christer Hogstrand
Researcher at King's College London
Publications - 347
Citations - 14664
Christer Hogstrand is an academic researcher from King's College London. The author has contributed to research in topics: Zinc & Metallothionein. The author has an hindex of 61, co-authored 323 publications receiving 11846 citations. Previous affiliations of Christer Hogstrand include European Food Safety Authority & University of Kentucky.
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Liver transcriptome analysis of Atlantic cod (Gadus morhua) exposed to PCB 153 indicates effects on cell cycle regulation and lipid metabolism
TL;DR: PCB 153 appears to activate cell proliferation and lipogenic genes in cod liver and Transcriptional up-regulation of marker genes for lipid biosynthesis resembles lipogenic effects previously reported for persistent organic pollutants (POPs) and other environmental chemicals.
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Activation of the rainbow trout metallothionein-A promoter by silver and zinc.
Gregory D. Mayer,Allan Leach,Peter Kling,Per-Erik Olsson,Christer Hogstrand,Christer Hogstrand,Christer Hogstrand +6 more
TL;DR: The hypothesis tested was that Ag activates the MT-A promoter indirectly by displacing Zn from pre-existing Zn-MT and that this liberated Zn subsequently induces MT synthesis, which indicates that Ag may be a direct inducer of MT.
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Functional expression of a low-affinity zinc uptake transporter (FrZIP2) from pufferfish (Takifugu rubripes) in MDCK cells.
Andong Qiu,Christer Hogstrand +1 more
TL;DR: Functional characterization suggests that FrZIP2 may be a prominent zinc uptake transporter of low affinity in many cell types of Fugu pufferfish and may employ a different mechanism of zinc translocation from the assumed HCO3--coupled zinc transport used by human SLC39A2.
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Sexual maturation and reproductive zinc physiology in the female squirrelfish.
E. David Thompson,Gregory D. Mayer,Patrick J. Walsh,Christer Hogstrand,Christer Hogstrand,Christer Hogstrand +5 more
TL;DR: It is demonstrated that female-specific zinc and MT accumulation and distribution are strongly correlated to the onset of sexual maturity in Holocentrus adsenscionis and VTG may not be the primary vehicle for hepato-ovarian zinc transport in squirrelfish.
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Acute and chronic physiological effects of silver exposure in three marine teleosts
TL;DR: The view that intestinal osmoregulatory function (drinking, Na(+)/K(+)-ATPase activity) is an important site of toxic impact for waterborne silver is reinforced, with chronic exposures at silver concentrations exert a variety of sublethal effects on marine teleosts.