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Christer Hogstrand

Researcher at King's College London

Publications -  347
Citations -  14664

Christer Hogstrand is an academic researcher from King's College London. The author has contributed to research in topics: Zinc & Metallothionein. The author has an hindex of 61, co-authored 323 publications receiving 11846 citations. Previous affiliations of Christer Hogstrand include European Food Safety Authority & University of Kentucky.

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Effect and mechanism of waterborne prolonged Zn exposure influencing hepatic lipid metabolism in javelin goby Synechogobius hasta

TL;DR: Evidence is provided that chronic Zn exposure differentially influenced mRNA expression and activities of genes and enzymes involved in lipogenic and lipolytic metabolism in a duration‐dependent manner, and new insight is provided into the relationship between metal elements and lipid metabolism.
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Expression of the ZIP/SLC39A transporters in β-cells: a systematic review and integration of multiple datasets.

TL;DR: ZIP6 and ZIP7 are proposed to be key functional orthologues in human and rodent β-cells and highlight these zinc importers as important targets for exploring associations between zinc status and normal physiology of β- cells and their decline in Type 2 Diabetes.
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Prolonged stimulation of insulin release from MIN6 cells causes zinc depletion and loss of β-cell markers.

TL;DR: The data suggest hyperglycaemia-induced zinc depletion may contribute to loss of β-cell markers and promote β- cell dedifferentiation through disrupting expression of key transcription factors.