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Christian Griesinger
Researcher at Max Planck Society
Publications - 449
Citations - 25595
Christian Griesinger is an academic researcher from Max Planck Society. The author has contributed to research in topics: Nuclear magnetic resonance spectroscopy & Residual dipolar coupling. The author has an hindex of 76, co-authored 408 publications receiving 23162 citations. Previous affiliations of Christian Griesinger include University of Göttingen & ETH Zurich.
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Journal ArticleDOI
Determination of 1J, 2J, and 3J Carbon-Carbon Coupling Constants at Natural Abundance
Journal ArticleDOI
Is Enantiomer Assignment Possible by NMR Spectroscopy Using Residual Dipolar Couplings from Chiral Nonracemic Alignment Media?—A Critical Assessment
Robert Berger,Jacques Courtieu,Roberto R. Gil,Christian Griesinger,Matthias Köck,Philippe Lesot,Burkhard Luy,Denis Merlet,Armando Navarro-Vázquez,Michael Reggelin,Uwe M. Reinscheid,Christina M. Thiele,Markus Zweckstetter +12 more
TL;DR: There is currently not a simple and universally applicable approach to determine the absolute configuration of molecules with few stereogenic centers, and two recent papers published in 2007 and 2011 have created a lot of excitement in the chemistry and NMR spectroscopy communities.
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Dipolar couplings in multiple alignments suggest alpha helical motion in ubiquitin.
TL;DR: RDCs of backbone N-HN vectors measured in 11 different alignment media are interpreted in terms of physically feasible cooperative reorientational motion of the helix with respect to the core of the protein to contradict neither NOE data nor molecular force-field calculations.
Journal ArticleDOI
Sequential correlation of anomeric ribose protons and intervening phosphorus in RNA oligonucleotides by a 1H,13C,31P triple resonance experiment: HCP-CCH-TOCSY
John P. Marino,Harald Schwalbe,Clemens Anklin,Wolfgang Bermel,Donald M. Crothers,Christian Griesinger +5 more
TL;DR: A three-dimensional 1H,13C,31P triple resonance experiment, HCP-CCH-TOCSY, is presented which provides unambiguous through-bond correlation of all 1H ribose protons on the 5′ and 3′ sides of the intervening phosphorus along the backbone bonding network in 13C-labeled RNA oligonucleotides.
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Determination of H(N),H (α) and H (N),C' coupling constants in (13)C, (15)N-labeled proteins.
Rüdiger Weisemann,Heinz Rüterjans,Harald Schwalbe,Schleucher J,Wolfgang Bermel,Christian Griesinger +5 more
TL;DR: Sensitive three-dimensional NMR experiments, based on the E.COSY principle, are presented for the measurement of the 3J(HN,Hα) and3J( HN,C′) coupling constants in uniformly 13C- and 15N-labeled proteins.