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Christian Griesinger

Researcher at Max Planck Society

Publications -  449
Citations -  25595

Christian Griesinger is an academic researcher from Max Planck Society. The author has contributed to research in topics: Nuclear magnetic resonance spectroscopy & Residual dipolar coupling. The author has an hindex of 76, co-authored 408 publications receiving 23162 citations. Previous affiliations of Christian Griesinger include University of Göttingen & ETH Zurich.

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The absolute configuration of dibromopalau'amine.

TL;DR: In this paper, the ensemble of conformations and the relative configuration of dibromopalau'amine by using NMR parameters such as 3 J couplings, ROEs and residual dipolar couplings were determined.
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A structural model of the complex formed by phospholamban and the calcium pump of sarcoplasmic reticulum obtained by molecular mechanics.

TL;DR: The model reveals that PLN does not span the entire width of the membrane, that is, its hydrophobic C‐terminal end is located near the center of the transmembrane region of the SERCA pump.
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Tau-induced mitochondrial membrane perturbation is dependent upon cardiolipin.

TL;DR: A scenario in which toxic cytosolic entities of tau protein would target mitochondrial organelles by associating with their CL-rich membrane domains, leading to membrane poration and compromised mitochondrial structural integrity is advanced.
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[ 11 C]MODAG-001-towards a PET tracer targeting α-synuclein aggregates

TL;DR: In this paper, a target-specific tracer to detect pathological aggregates of α-synuclein (αSYN) remains lacking, and a positron emission tomography (PET) tracer based on anle138b, a compound shown to have therapeutic activity in animal models of neurodegenerative diseases.