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Christian Griesinger
Researcher at Max Planck Society
Publications - 449
Citations - 25595
Christian Griesinger is an academic researcher from Max Planck Society. The author has contributed to research in topics: Nuclear magnetic resonance spectroscopy & Residual dipolar coupling. The author has an hindex of 76, co-authored 408 publications receiving 23162 citations. Previous affiliations of Christian Griesinger include University of Göttingen & ETH Zurich.
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Aromaticity at position 39 in α‐synuclein: A modulator of amyloid fibril assembly and membrane‐bound conformations
Fiamma Buratti,Nicola Boeffinger,Hugo A. Garro,Jesica S. Flores,Francisco Javier Hita,Phelippe do Carmo Gonçalves,Federico Dos Reis Copello,Leonardo Lizarraga,Giulia Rossetti,Paolo Carloni,Markus Zweckstetter,Tiago F. Outeiro,Stefan Eimer,Christian Griesinger,Claudio O. Fernández +14 more
TL;DR: It is demonstrated that aromaticity at position 39 of αS primary sequence influences strongly the aggregation properties and the membrane‐bound conformations of the protein, molecular features that might have important repercussions for the function and dysfunction ofαS.
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Deformation and phase transformation in polycrystalline cementite (Fe3C) during single- and multi-pass sliding wear
H. Tsybenko,Chunhua Tian,Julia S. Rau,Benjamin Breitbach,Paul Schreiber,Christian Griesinger,Gerhard Dehm,Steffen Brinckmann +7 more
TL;DR: In this article , the deformation and chemical evolution of bulk polycrystalline cementite during single pass sliding at a contact pressure of 31 GPa and reciprocating multi-pass sliding at 3.3 GPa were investigated.
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Combinatorial synthesis of cholesterol ester transfer protein-mRNA ligands and screening by nondenaturating gel-electrophoresis.
TL;DR: Employing combinatorial chemistry methods, small peptide ligands were found, which bind to a short RNA with important biological functions, which are an attractive therapeutic target.
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Low-Expressing Synucleinopathy Mouse Models Based on Oligomer-Forming Mutations and C-Terminal Truncation of α-Synuclein.
Ana Martinez Hernandez,Ivan Silbern,Ivan Silbern,Insa Geffers,Lars Tatenhorst,Stefan Becker,Henning Urlaub,Henning Urlaub,Markus Zweckstetter,Markus Zweckstetter,Markus Zweckstetter,Christian Griesinger,Christian Griesinger,Gregor Eichele +13 more
TL;DR: In this paper, two mouse models for synucleinopathy based on a triple alanine to proline mutation and a C-terminal truncation of α-synuclein (αSyn) were reported.
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1H, 13C and 15N resonance assignments of the Calmodulin-Munc13-1 peptide complex.
Fernando Rodriguez-Castañeda,Nicolas Coudevylle,Stefan Becker,Nils Brose,Teresa Carlomagno,Christian Griesinger +5 more
TL;DR: Ca2+-Calmodulin binding to the variable N-terminal region of the diacylglycerol/phorbol ester-binding UNC13/Munc13 family of proteins modulates the short-term synaptic plasticity characteristics in neurons.