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Christianne N. Heck
Researcher at University of Southern California
Publications - 43
Citations - 3426
Christianne N. Heck is an academic researcher from University of Southern California. The author has contributed to research in topics: Epilepsy & Responsive neurostimulation device. The author has an hindex of 20, co-authored 36 publications receiving 2745 citations. Previous affiliations of Christianne N. Heck include United States Department of Veterans Affairs & University of California, Los Angeles.
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Journal ArticleDOI
Two‐year seizure reduction in adults with medically intractable partial onset epilepsy treated with responsive neurostimulation: Final results of the RNS System Pivotal trial
Christianne N. Heck,David King-Stephens,Andrew Massey,Dileep Nair,Barbara C. Jobst,Gregory L. Barkley,Vicenta Salanova,Andrew J. Cole,Michael C. Smith,Ryder P. Gwinn,Christopher Skidmore,Paul C. Van Ness,Gregory K. Bergey,Yong D. Park,Ian Miller,Eric B. Geller,Paul Rutecki,Richard S. Zimmerman,David C. Spencer,Alica M. Goldman,Jonathan C. Edwards,James W. Leiphart,Robert E. Wharen,James Fessler,Nathan B. Fountain,Gregory A. Worrell,Robert E. Gross,Stephan Eisenschenk,Robert B. Duckrow,Lawrence J. Hirsch,Carl W. Bazil,Cormac A. O'Donovan,Felice T. Sun,Tracy A. Courtney,Cairn G. Seale,Martha J. Morrell +35 more
TL;DR: To demonstrate the safety and effectiveness of responsive stimulation at the seizure focus as an adjunctive therapy to reduce the frequency of seizures in adults with medically intractable partial onset seizures arising from one or two seizure foci.
Journal ArticleDOI
Long-term treatment with responsive brain stimulation in adults with refractory partial seizures
Gregory K. Bergey,Martha J. Morrell,Eli M. Mizrahi,Alica M. Goldman,David King-Stephens,Dileep Nair,Shraddha Srinivasan,Barbara C. Jobst,Robert E. Gross,Donald C. Shields,Gregory L. Barkley,Vicenta Salanova,Piotr W. Olejniczak,Andrew J. Cole,Sydney S. Cash,Katherine H. Noe,Robert E. Wharen,Gregory A. Worrell,Anthony M. Murro,Jonathan C. Edwards,Michael Duchowny,David C. Spencer,Michael C. Smith,Eric B. Geller,Ryder P. Gwinn,Christopher Skidmore,Stephan Eisenschenk,Michel J. Berg,Christianne N. Heck,Paul C. Van Ness,Nathan B. Fountain,Paul Rutecki,Andrew Massey,Cormac A. O'Donovan,Douglas Labar,Robert B. Duckrow,Lawrence J. Hirsch,Tracy A. Courtney,Felice T. Sun,Cairn G. Seale +39 more
TL;DR: This study provides Class IV evidence that for adults with medically refractory partial onset seizures, responsive direct cortical stimulation reduces seizures and improves quality of life over a mean follow-up of 5.4 years.
Journal ArticleDOI
Prospective Long-Term Study of Vagus Nerve Stimulation for the Treatment of Refractory Seizures
Christopher M. DeGiorgio,Steven C. Schachter,Adrian Handforth,Martin C. Salinsky,J. Thompson,Basim M. Uthman,Robin Reed,S. Collin,Evelyn S. Tecoma,George L. Morris,Bradley V. Vaughn,Dean K. Naritoku,Thomas R. Henry,Thomas R. Henry,D. Labar,R. C. Gilmartin,D. Labiner,Ivan Osorio,R. Ristanovic,R. Ristanovic,Jana E. Jones,Jerome V. Murphy,G. C. Ney,J. Wheless,P. Lewis,Christianne N. Heck +25 more
TL;DR: In this paper, the authors report the largest prospective long-term study of VNS to date, showing that VNS improves during 12 months, and many subjects sustain >75% reductions in seizures.
Journal ArticleDOI
Brain-responsive neurostimulation in patients with medically intractable mesial temporal lobe epilepsy
Eric B. Geller,Tara L. Skarpaas,Robert E. Gross,Robert R. Goodman,Gregory L. Barkley,Carl W. Bazil,Michael J. Berg,Gregory K. Bergey,Sydney S. Cash,Andrew J. Cole,Robert B. Duckrow,Jonathan C. Edwards,Stephan Eisenschenk,James Fessler,Nathan B. Fountain,Alicia M. Goldman,Ryder P. Gwinn,Christianne N. Heck,Aamar Herekar,Lawrence J. Hirsch,Barbara C. Jobst,David King-Stephens,Douglas Labar,James W. Leiphart,W. Richard Marsh,Kimford J. Meador,Eli M. Mizrahi,Anthony M. Murro,Dileep Nair,Katherine H. Noe,Yong D. Park,Paul Rutecki,Vicenta Salanova,Raj D. Sheth,Donald C. Shields,Christopher Skidmore,Michael C. Smith,David C. Spencer,Shraddha Srinivasan,William O. Tatum,Paul C. Van Ness,David G. Vossler,Robert E. Wharen,Gregory A. Worrell,Daniel Yoshor,Richard S. Zimmerman,Kathy Cicora,Felice T. Sun,Martha J. Morrell +48 more
TL;DR: In this paper, the authors evaluated the seizure-reduction response and safety of brain-responsive stimulation in adults with medically intractable partial-onset seizures of mesial temporal lobe origin.
Journal ArticleDOI
Lateralization of mesial temporal lobe epilepsy with chronic ambulatory electrocorticography
David King-Stephens,Emily A. Mirro,Peter B. Weber,Kenneth D. Laxer,Paul C. Van Ness,Vicenta Salanova,David C. Spencer,Christianne N. Heck,Alica M. Goldman,Barbara C. Jobst,Donald C. Shields,Gregory K. Bergey,Stephan Eisenschenk,Gregory A. Worrell,Marvin A. Rossi,Robert E. Gross,Andrew J. Cole,Michael R. Sperling,Dileep Nair,Ryder P. Gwinn,Yong D. Park,Paul Rutecki,Nathan B. Fountain,Robert E. Wharen,Lawrence J. Hirsch,Ian Miller,Gregory L. Barkley,Jonathan C. Edwards,Eric B. Geller,Michel J. Berg,Toni Sadler,Felice T. Sun,Martha J. Morrell +32 more
TL;DR: In this article, the authors describe data obtained from chronic ambulatory ECoG in patients with suspected bilateral MTL epilepsy in order to assess the time required to determine the seizure lateralization and whether this information could influence treatment decisions.