Christoph H. Weinert

TL;DR: A methodological description of nutritional metabolomics is provided that reflects on the state-of-the-art techniques used in the laboratories of the Food Biomarker Alliance as well as points of reflections to harmonize this field.

TL;DR: The metabolite profile of human urine and plasma allows the prediction of sex and age with high accuracy, which means thatsex and age are associated with a discriminatory metabolite signature in healthy humans and therefore should always be considered in metabolomics studies.

TL;DR: In the current analysis two different tomato genotypes were analysed by untargeted comprehensive two-dimensional gas chromatography mass spectrometry (GC×GC-MS), this analysis revealed clear differences in the metabolic profiles which were paralleled by differences in resistance towards Alternaria colonization.

TL;DR: The GC×GC-qMS system proved to be applicable for untargeted large scale metabolome analyses by the analysis of more than 300 human urine study samples for which detailed repeatability and intermediate precision data are provided.

TL;DR: The results indicate that the degree and position of methylation depend clearly on the three-dimensional structure of the entire substrate molecule.