C
Christopher Vollmers
Researcher at University of California, Santa Cruz
Publications - 71
Citations - 6263
Christopher Vollmers is an academic researcher from University of California, Santa Cruz. The author has contributed to research in topics: Transcriptome & Gene. The author has an hindex of 25, co-authored 61 publications receiving 4867 citations. Previous affiliations of Christopher Vollmers include Stanford University & Heidelberg University.
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Journal ArticleDOI
Time-Restricted Feeding without Reducing Caloric Intake Prevents Metabolic Diseases in Mice Fed a High-Fat Diet
Megumi Hatori,Christopher Vollmers,Amir Zarrinpar,Amir Zarrinpar,Luciano DiTacchio,Eric A. Bushong,Shubhroz Gill,Mathias Leblanc,Amandine Chaix,Matthew S. Joens,James A. J. Fitzpatrick,Mark H. Ellisman,Satchidananda Panda +12 more
TL;DR: Mice under tRF consume equivalent calories from HFD as those with ad lib access yet are protected against obesity, hyperinsulinemia, hepatic steatosis, and inflammation and have improved motor coordination.
Journal ArticleDOI
Time of feeding and the intrinsic circadian clock drive rhythms in hepatic gene expression.
Christopher Vollmers,Shubhroz Gill,Luciano DiTacchio,Sandhya R. Pulivarthy,Hiep D. Le,Satchidananda Panda +5 more
TL;DR: It is shown that both temporal pattern of food intake and the circadian clock drive rhythmic transcription, thereby highlighting temporal regulation of hepatic transcription as an emergent property of the circadian system.
Journal ArticleDOI
Harmonics of Circadian Gene Transcription in Mammals
Michael E. Hughes,Luciano DiTacchio,Kevin R. Hayes,Christopher Vollmers,S. Pulivarthy,Julie E. Baggs,Satchidananda Panda,John B. Hogenesch +7 more
TL;DR: These studies illustrate the importance of time sampling with respect to multiple testing, suggest caution in use of autonomous cellular models to study clock output, and demonstrate the existence of harmonics of circadian gene expression in the mouse.
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Nanopore long-read RNAseq reveals widespread transcriptional variation among the surface receptors of individual B cells
Ashley Byrne,Anna E. Beaudin,Hugh E. Olsen,Miten Jain,Charles Cole,Theron Palmer,Rebecca M. DuBois,E. Camilla Forsberg,Mark Akeson,Christopher Vollmers +9 more
TL;DR: This work investigates whether RNAseq using the long-read single-molecule Oxford Nanopore MinION sequencer is able to identify and quantify complex isoforms without sacrificing accurate gene expression quantification, and shows that it can identify and quantify complexisoforms at the single cell level.
Journal ArticleDOI
Inducible ablation of melanopsin-expressing retinal ganglion cells reveals their central role in non-image forming visual responses.
Megumi Hatori,Hiep D. Le,Christopher Vollmers,Sheena Racheal Keding,Nobushige Tanaka,Christian Schmedt,Timothy Jegla,Satchidananda Panda +7 more
TL;DR: The results point to the mRGCs as the site of functional integration of the rod/cone and melanopsin phototransduction pathways and as the primary anatomical site for the divergence of image-forming and non-image forming photoresponses in mammals.